Yeast as a Tool to Understand the Significance of Human Disease-Associated Gene Variants

by Tiziana Cervelli, Alvaro Galli
Published 2021-08-01

Formation of AAV single stranded DNA genome from a circular plasmid in Saccharomyces cerevisiae.

by Tiziana Cervelli, Ana Backovic, Alvaro Galli
Published 2011-01-01

Inhibition of DNA Repair in Cancer Therapy: Toward a Multi-Target Approach

by Samuele Lodovichi, Tiziana Cervelli, Achille Pellicioli, Alvaro Galli
Published 2020-09-01

Yeast-based assays for the functional characterization of cancer-associated variants of human DNA repair genes

by Tiziana Cervelli, Samuele Lodovichi, Francesca Bellè, Alvaro Galli
Published 2020-05-01

The Over-expression of the β2 Catalytic Subunit of the Proteasome Decreases Homologous Recombination and Impairs DNA Double-Strand Break Repair in Human Cells

by Anita Collavoli, Laura Comelli, Tiziana Cervelli, Alvaro Galli
Published 2011-01-01

The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent

by Alvaro Galli, Kurt Hafer, Tiziana Cervelli, Robert H. Schiestl
Published 2009-01-01

DNA Damage and Repair in Atherosclerosis: Current Insights and Future Perspectives

by Maria Grazia Andreassi, Andrea Borghini, Alvaro Galli, Tiziana Cervelli
Published 2012-12-01

Expression of bovine cytosolic 5'-nucleotidase (cN-II) in yeast: nucleotide pools disturbance and its consequences on growth and homologous recombination.

by Simone Allegrini, Daniela Nicole Filoni, Alvaro Galli, Anita Collavoli, Rossana Pesi, Marcella Camici, Maria Grazia Tozzi
Published 2013-01-01

Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf.

by Federico Cividini, Maria Grazia Tozzi, Alvaro Galli, Rossana Pesi, Marcella Camici, Charles Dumontet, Lars Petter Jordheim, Simone Allegrini
Published 2015-01-01

Effects of germline and somatic events in candidate BRCA-like genes on breast-tumor signatures

by Weston R. Bodily, Brian H. Shirts, Tom Walsh, Suleyman Gulsuner, Mary-Claire King, Alyssa Parker, Moom Roosan, Stephen R. Piccolo, Alvaro Galli
Published 2020-01-01

Impact of mutations in homologous recombination repair genes on treatment outcomes for metastatic castration resistant prostate cancer

by Alexander S. Carlson, Rigo I. Acevedo, Daniel M. Lim, Roman Gulati, Agnes Gawne, Alexandra O. Sokolova, Heather H. Cheng, Peter S. Nelson, R. Bruce Montgomery, Evan Y. Yu, Michael T. Schweizer, Alvaro Galli
Published 2020-01-01

Functional Interaction Between BRCA1 and DNA Repair in Yeast May Uncover a Role of RAD50, RAD51, MRE11A, and MSH6 Somatic Variants in Cancer Development

by Luisa Maresca, Samuele Lodovichi, Samuele Lodovichi, Alessandra Lorenzoni, Tiziana Cervelli, Rossella Monaco, Laura Spugnesi, Mariella Tancredi, Elisabetta Falaschi, Katia Zavaglia, Elisabetta Landucci, Manuela Roncella, Caterina Congregati, Angiolo Gadducci, Antonio Giuseppe Naccarato, Maria Adelaide Caligo, Alvaro Galli
Published 2018-09-01

Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

by Craig B Bennett, Tammy J Westmoreland, Carmel S Verrier, Carrie A B Blanchette, Tiffany L Sabin, Hemali P Phatnani, Yuliya V Mishina, Gudrun Huper, Alice L Selim, Ernest R Madison, Dominique D Bailey, Adebola I Falae, Alvaro Galli, John A Olson, Arno L Greenleaf, Jeffrey R Marks
Published 2008-01-01

Detection of Germline Variants in 450 Breast/Ovarian Cancer Families with a Multi-Gene Panel Including Coding and Regulatory Regions

by Chiara Guglielmi, Rosa Scarpitta, Gaetana Gambino, Eleonora Conti, Francesca Bellè, Mariella Tancredi, Tiziana Cervelli, Elisabetta Falaschi, Cinzia Cosini, Paolo Aretini, Caterina Congregati, Marco Marino, Margherita Patruno, Brunella Pilato, Francesca Spina, Luisa Balestrino, Elena Tenedini, Ileana Carnevali, Laura Cortesi, Enrico Tagliafico, Maria Grazia Tibiletti, Stefania Tommasi, Matteo Ghilli, Caterina Vivanet, Alvaro Galli, Maria Adelaide Caligo
Published 2021-07-01