MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity.

by Mark Yarchoan, Aditya A Mohan, Lauren Dennison, Teena Vithayathil, Amanda Ruggieri, Gregory B Lesinski, Todd D Armstrong, Nilofer S Azad, Elizabeth M Jaffee
Published 2019-01-01

330 Investigating the clinical safety, efficacy, and immune modulation of combined XL888 and pembrolizumab in metastatic gastrointestinal malignancies

by Mohammad Zaidi, Yuchen Zhang, Kavita Dhodapkar, Madhav Dhodapkar, Gregory Lesinski, Matthew Farren, Christina Wu, Rafi Ahmed, Cameron Herting, Deon Doxie, Michael Ware, Olatunji Alese, Walid Shaib, Mehmet Akce, Amanda Ruggieri, Juan Sarmiento, Shishir Maithel, Bassel El-rayes
Published 2020-11-01