Removal of the C-Terminal Domains of ADAMTS13 by Activated Coagulation Factor XI induces Platelet Adhesion on Endothelial Cells under Flow Conditions

by Kathleen S. Garland, Kathleen S. Garland, Stéphanie E. Reitsma, Stéphanie E. Reitsma, Toshiaki Shirai, Jevgenia Zilberman-Rudenko, Erik I. Tucker, Erik I. Tucker, David Gailani, András Gruber, András Gruber, Owen J. T. McCarty, Cristina Puy
Published 2017-12-01

Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI.

by Cristina Puy, Erik I Tucker, Ivan S Ivanov, David Gailani, Stephanie A Smith, James H Morrissey, András Gruber, Owen J T McCarty
Published 2016-01-01

Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice.

by Charles E Bane, Ivan Ivanov, Anton Matafonov, Kelli L Boyd, Qiufang Cheng, Edward R Sherwood, Erik I Tucker, Stephen T Smiley, Owen J T McCarty, Andras Gruber, David Gailani
Published 2016-01-01

Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates

by Michael Wallisch, Christina U. Lorentz, Hari H. S. Lakshmanan, Jennifer Johnson, Marschelle R. Carris, Cristina Puy, David Gailani, Monica T. Hinds, Owen J. T. McCarty, András Gruber, Erik I. Tucker
Published 2020-02-01

The contact activation system as a potential therapeutic target in patients with COVID‐19

by Joseph J. Shatzel, Emma P. DeLoughery, Christina U. Lorentz, Erik I. Tucker, Joseph E. Aslan, Monica T. Hinds, David Gailani, Jeffrey I. Weitz, Owen J. T. McCarty, Andras Gruber
Published 2020-05-01