Cell Senescence, Multiple Organelle Dysfunction and Atherosclerosis

by Gisela Machado-Oliveira, Cristiano Ramos, André R. A. Marques, Otília V. Vieira
Published 2020-09-01

Lysosome (Dys)function in Atherosclerosis—A Big Weight on the Shoulders of a Small Organelle

by André R. A. Marques, Cristiano Ramos, Gisela Machado-Oliveira, Otília V. Vieira
Published 2021-03-01

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

by Vincenzo Sorrentino, Jessica K. Nelson, Elena Maspero, André R.A. Marques, Lilith Scheer, Simona Polo, Noam Zelcer
Published 2013-08-01

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease.

by André R A Marques, Tanit L Gabriel, Jan Aten, Cindy P A A van Roomen, Roelof Ottenhoff, Nike Claessen, Pilar Alfonso, Pilar Irún, Pilar Giraldo, Johannes M F G Aerts, Marco van Eijk
Published 2016-01-01

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

by Martijn J. C. van der Lienden, Jan Aten, André R. A. Marques, Ingeborg S. E. Waas, Per W. B. Larsen, Nike Claessen, Nicole N. van der Wel, Roelof Ottenhoff, Marco van Eijk, Johannes M. F. G. Aerts
Published 2021-03-01

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain

by Eva J. van Rooden, Annelot C. M. van Esbroeck, Marc P. Baggelaar, Hui Deng, Bogdan I. Florea, André R. A. Marques, Roelof Ottenhoff, Rolf G. Boot, Herman S. Overkleeft, Johannes M. F. G. Aerts, Mario van der Stelt
Published 2018-07-01

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.

by André R A Marques, Jan Aten, Roelof Ottenhoff, Cindy P A A van Roomen, Daniela Herrera Moro, Nike Claessen, María Fernanda Vinueza Veloz, Kuikui Zhou, Zhanmin Lin, Mina Mirzaian, Rolf G Boot, Chris I De Zeeuw, Herman S Overkleeft, Yildiz Yildiz, Johannes M F G Aerts
Published 2015-01-01

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes.

by Daniela Herrera Moro Chao, Wouter W Kallemeijn, Andre R A Marques, Marie Orre, Roelof Ottenhoff, Cindy van Roomen, Ewout Foppen, Maria C Renner, Martina Moeton, Marco van Eijk, Rolf G Boot, Willem Kamphuis, Elly M Hol, Jan Aten, Hermen S Overkleeft, Andries Kalsbeek, Johannes M F G Aerts
Published 2015-01-01

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases[S]

by AndréR.A. Marques, Mina Mirzaian, Hisako Akiyama, Patrick Wisse, Maria J. Ferraz, Paulo Gaspar, Karen Ghauharali-van der Vlugt, Rianne Meijer, Pilar Giraldo, Pilar Alfonso, Pilar Irún, Maria Dahl, Stefan Karlsson, Elena V. Pavlova, Timothy M. Cox, Saskia Scheij, Marri Verhoek, Roelof Ottenhoff, CindyP.A.A. van Roomen, Navraj S. Pannu, Marco van Eijk, Nick Dekker, Rolf G. Boot, Herman S. Overkleeft, Edward Blommaart, Yoshio Hirabayashi, Johannes M. Aerts
Published 2016-03-01