HLA-DM mediates epitope selection by a "compare-exchange" mechanism when a potential peptide pool is available.

by Andrea Ferrante, Matthew W Anderson, Candice S Klug, Jack Gorski
Published 2008-01-01

A structure-based engineering approach to abrogate pre-existing antibody binding to biotherapeutics.

by Joanne Lin, Stacey L Lee, Anna M Russell, Rong Fong Huang, Micheal A Batt, Shawn S Chang, Andrea Ferrante, Petra Verdino
Published 2021-01-01

A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins

by Andrzej M. Kierzek, Timothy P. Hickling, Isabel Figueroa, J. Cory Kalvass, Marjoleen Nijsen, Krithika Mohan, Geertruida M. Veldman, Akihiro Yamada, Hiroyuki Sayama, Sachiko Yokoo, Abhishek Gulati, Renu S. Dhanikula, Jochem Gokemeijer, Tarek A. Leil, Craig J. Thalhauser, Mario Giorgi, Maciej J. Swat, Vijayalakshmi Chelliah, Ben G. Small, Neil Benson, Michael Walker, Kapil Gadkar, Valerie Quarmby, Rong Deng, Andrea Ferrante, Gemma L. Dickinson, Jan‐Stefan Van Der Walt, Lian Zhou, Xiaoying Chen, Hannah M. Jones, Jatin Narula, Sophie Tourdot, Thierry Lavé, Benjamin Ribba, Piet H. van derGraaf
Published 2019-11-01