The balance between mitotic death and mitotic slippage in acute leukemia: a new therapeutic window?

by Andrea Ghelli Luserna di Rorà, Giovanni Martinelli, Giorgia Simonetti
Published 2019-11-01

A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target

by Andrea Ghelli Luserna di Rorà, Claudio Cerchione, Giovanni Martinelli, Giorgia Simonetti
Published 2020-09-01

Axitinib in Ponatinib-Resistant B-Cell Acute Lymphoblastic Leukemia Harboring a T315L Mutation

by Valentina Giudice, Andrea Ghelli Luserna di Rorà, Bianca Serio, Roberto Guariglia, Maria Benedetta Giannini, Anna Ferrari, Giorgia Simonetti, Carmine Selleri, Giovanni Martinelli
Published 2020-12-01

Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents

by Giorgia Simonetti, Carla Boga, Joseph Durante, Gabriele Micheletti, Dario Telese, Paolo Caruana, Andrea Ghelli Luserna di Rorà, Fabio Mantellini, Samantha Bruno, Giovanni Martinelli, Natalia Calonghi
Published 2021-01-01

Therapeutic Targeting of Acute Myeloid Leukemia by Gemtuzumab Ozogamicin

by Michele Gottardi, Giorgia Simonetti, Alessandra Sperotto, Davide Nappi, Andrea Ghelli Luserna di Rorà, Antonella Padella, Marianna Norata, Maria Benedetta Giannini, Gerardo Musuraca, Francesco Lanza, Claudio Cerchione, Giovanni Martinelli
Published 2021-09-01

Loss of PALB2 predicts poor prognosis in acute myeloid leukemia and suggests novel therapeutic strategies targeting the DNA repair pathway

by Antonella Padella, Maria Chiara Fontana, Giovanni Marconi, Eugenio Fonzi, Elisabetta Petracci, Anna Ferrari, Carmen Baldazzi, Cristina Papayannidis, Andrea Ghelli Luserna Di Rorá, Nicoletta Testoni, Gastone Castellani, Torsten Haferlach, Giovanni Martinelli, Giorgia Simonetti
Published 2021-01-01

Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients

by Serena De Matteis, Chiara Molinari, Giulia Abbati, Tania Rossi, Roberta Napolitano, Martina Ghetti, Andrea Ghelli Luserna Di Rorà, Gerardo Musuraca, Alessandro Lucchesi, Gian Matteo Rigolin, Antonio Cuneo, Daniele Calistri, Pier Paolo Fattori, Massimiliano Bonafè, Giovanni Martinelli
Published 2018-06-01

CART-Cell Therapy: Recent Advances and New Evidence in Multiple Myeloma

by Massimo Martino, Filippo Antonio Canale, Caterina Alati, Iolanda Donatella Vincelli, Tiziana Moscato, Gaetana Porto, Barbara Loteta, Virginia Naso, Massimiliano Mazza, Fabio Nicolini, Andrea Ghelli Luserna di Rorà, Giorgia Simonetti, Sonia Ronconi, Michela Ceccolini, Gerardo Musuraca, Giovanni Martinelli, Claudio Cerchione
Published 2021-05-01

Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia

by Andrea Ghelli Luserna Di Rorà, Matteo Bocconcelli, Anna Ferrari, Carolina Terragna, Samantha Bruno, Enrica Imbrogno, Neil Beeharry, Valentina Robustelli, Martina Ghetti, Roberta Napolitano, Gabriella Chirumbolo, Giovanni Marconi, Cristina Papayannidis, Stefania Paolini, Chiara Sartor, Giorgia Simonetti, Timothy J. Yen, Giovanni Martinelli
Published 2019-10-01

Combined Oral Fentanyl Citrate and Midazolam as Premedication for Bone Marrow Aspiration and Biopsy in Patients with Hematological Malignancies: A Randomized, Controlled and Patien...

by Claudio Cerchione, Giovanni Martinelli, Marco Picardi, Novella Pugliese, Davide Nappi, Aniello Casoria, Angela Gravetti, Delia Cangini, Maria Benedetta Giannini, Sonia Ronconi, Giorgia Simonetti, Andrea Ghelli Luserna Di Rorà, Ugo De Giorgi, Mattia Altini, Sara Bravaccini, Ilaria Santoriello, Cristiano Minucci, Fabrizio Pane, Vincenzo Martinelli
Published 2020-02-01

Pharmacological Inhibition of WIP1 Sensitizes Acute Myeloid Leukemia Cells to the MDM2 Inhibitor Nutlin-3a

by Maria Chiara Fontana, Jacopo Nanni, Andrea Ghelli Luserna di Rorà, Elisabetta Petracci, Antonella Padella, Martina Ghetti, Anna Ferrari, Giovanni Marconi, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Antonio Curti, Ernesta Audisio, Maria Benedetta Giannini, Michela Rondoni, Francesco Lanza, Michele Cavo, Giovanni Martinelli, Giorgia Simonetti
Published 2021-04-01

Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia

by Samantha Bruno, Maria Teresa Bochicchio, Eugenia Franchini, Antonella Padella, Giovanni Marconi, Andrea Ghelli Luserna di Rorà, Claudia Venturi, Maddalena Raffini, Giovanna Prisinzano, Anna Ferrari, Lorenza Bandini, Valentina Robustelli, Martina Pazzaglia, Maria Chiara Fontana, Chiara Sartor, Maria Chiara Abbenante, Cristina Papayannidis, Simona Soverini, Emanuela Ottaviani, Giorgia Simonetti, Giovanni Martinelli
Published 2019-01-01

Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia

by Andrea Ghelli Luserna Di Rorà, Neil Beeharry, Enrica Imbrogno, Anna Ferrari, Valentina Robustelli, Simona Righi, Elena Sabattini, Maria Vittoria Verga Falzacappa, Chiara Ronchini, Nicoletta Testoni, Carmen Baldazzi, Cristina Papayannidis, Maria Chiara Abbenante, Giovanni Marconi, Stefania Paolini, Sarah Parisi, Chiara Sartor, Maria Chiara Fontana, Serena De Matteis, Ilaria Iacobucci, Pier Giuseppe Pelicci, Michele Cavo, Timothy J. Yen, Giovanni Martinelli
Published 2018-08-01

Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers for T-cell acute lymphoblastic leukemia

by Daniele Caracciolo, Antonio Giordano, Pierfrancesco Tassone, Caterina Riillo, Andrea Ballerini, Giuseppe Gaipa, Ludovic Lhermitte, Marco Rossi, Eugénie Duroyon, Katia Grillone, Maria Eugenia Gallo Cantafio, Chiara Buracchi, Greta Alampi, Alessandro Gulino, Beatrice Belmonte, Francesco Conforti, Gaetanina Golino, Giada Juli, Emanuela Altomare, Nicoletta Polerà, Francesca Scionti, Mariamena Arbitrio, Michelangelo Iannone, Massimo Martino, Gabriella Talarico, Andrea Ghelli Luserna di Rorà, Anna Ferrari, Simona Sestito, Licia Pensabene, Markus Hildinger, Maria Teresa Di Martino, Giovanni Martinelli, Claudio Tripodo, Vahid Asnafi
Published 2021-02-01