Proximal Cysteines that Enhance Lysine N-Acetylation of Cytosolic Proteins in Mice Are Less Conserved in Longer-Living Species

by Andrew M. James, Anthony C. Smith, Cassandra L. Smith, Alan J. Robinson, Michael P. Murphy
Published 2018-08-01

Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II

by Andrew M. James, Kurt Hoogewijs, Angela Logan, Andrew R. Hall, Shujing Ding, Ian M. Fearnley, Michael P. Murphy
Published 2017-02-01

Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster

by Katja E. Menger, Andrew M. James, Helena M. Cochemé, Michael E. Harbour, Edward T. Chouchani, Shujing Ding, Ian M. Fearnley, Linda Partridge, Michael P. Murphy
Published 2015-06-01

Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster

by Katja E. Menger, Andrew M. James, Helena M. Cochemé, Michael E. Harbour, Edward T. Chouchani, Shujing Ding, Ian M. Fearnley, Linda Partridge, Michael P. Murphy
Published 2015-11-01

Structural basis for a complex I mutation that blocks pathological ROS production

by Zhan Yin, Nils Burger, Duvaraka Kula-Alwar, Dunja Aksentijević, Hannah R. Bridges, Hiran A. Prag, Daniel N. Grba, Carlo Viscomi, Andrew M. James, Amin Mottahedin, Thomas Krieg, Michael P. Murphy, Judy Hirst
Published 2021-01-01

Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma.

by Brian Cunniff, Kheng Newick, Kimberly J Nelson, Alexandra N Wozniak, Stacie Beuschel, Bruce Leavitt, Anant Bhave, Kelly Butnor, Andreas Koenig, Edward T Chouchani, Andrew M James, Alexina C Haynes, W Todd Lowther, Michael P Murphy, Arti Shukla, Nicholas H Heintz
Published 2015-01-01

Malonylation of GAPDH is an inflammatory signal in macrophages

by Silvia Galván-Peña, Richard G. Carroll, Carla Newman, Elizabeth C. Hinchy, Eva Palsson-McDermott, Elektra K. Robinson, Sergio Covarrubias, Alan Nadin, Andrew M. James, Moritz Haneklaus, Susan Carpenter, Vincent P. Kelly, Michael P. Murphy, Louise K. Modis, Luke A. O’Neill
Published 2019-01-01

Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury

by Timothy E. Beach, Hiran A. Prag, Laura Pala, Angela Logan, Margaret M. Huang, Anja V. Gruszczyk, Jack L. Martin, Krishnaa Mahbubani, Mazin O. Hamed, Sarah A. Hosgood, Michael L. Nicholson, Andrew M. James, Richard C. Hartley, Michael P. Murphy, Kourosh Saeb-Parsy
Published 2020-09-01