Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects

by Ana Rolo, Gabriel L. Galea, Dawn Savery, Nicholas D. E. Greene, Andrew J. Copp
Published 2019-11-01

Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

by Kit-Yi Leung, Sandra C. P. De Castro, Gabriel L. Galea, Andrew J. Copp, Nicholas D. E. Greene
Published 2021-01-01

Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice

by Gabriel L. Galea, Eirini Maniou, Timothy J. Edwards, Abigail R. Marshall, Ioakeim Ampartzidis, Nicholas D. E. Greene, Andrew J. Copp
Published 2021-02-01

Author Correction: Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice

by Gabriel L. Galea, Eirini Maniou, Timothy J. Edwards, Abigail R. Marshall, Ioakeim Ampartzidis, Nicholas D. E. Greene, Andrew J. Copp
Published 2021-05-01

Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

by Jennifer N. Murdoch, Christine Damrau, Anju Paudyal, Debora Bogani, Sara Wells, Nicholas D. E. Greene, Philip Stanier, Andrew J. Copp
Published 2014-10-01

Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice.

by Sandra C P De Castro, Ashraf Malhas, Kit-Yi Leung, Peter Gustavsson, David J Vaux, Andrew J Copp, Nicholas D E Greene
Published 2012-01-01

Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos

by Gabriel L. Galea, Oleksandr Nychyk, Matteo A. Mole, Dale Moulding, Dawn Savery, Evanthia Nikolopoulou, Deborah J. Henderson, Nicholas D. E. Greene, Andrew J. Copp
Published 2018-03-01

Regulation of cell protrusions by small GTPases during fusion of the neural folds

by Ana Rolo, Dawn Savery, Sarah Escuin, Sandra C de Castro, Hannah EJ Armer, Peter MG Munro, Matteo A Molè, Nicholas DE Greene, Andrew J Copp
Published 2016-04-01

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2

by Evanthia Nikolopoulou, Caroline S. Hirst, Gabriel Galea, Christina Venturini, Dale Moulding, Abigail R. Marshall, Ana Rolo, Sandra C. P. De Castro, Andrew J. Copp, Nicholas D. E. Greene
Published 2019-06-01

Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure

by Kit-Yi Leung, Yun Jin Pai, Qiuying Chen, Chloe Santos, Enrica Calvani, Sonia Sudiwala, Dawn Savery, Markus Ralser, Steven S. Gross, Andrew J. Copp, Nicholas D.E. Greene
Published 2017-11-01

Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice

by Timothy Mohun, David J. Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Myriam Hemberger, Corinne Houart, Matt E. Hurles, Elizabeth Robertson, James C. Smith, Tom Weaver, Wolfgang Weninger
Published 2013-05-01

Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid

by Sonia Sudiwala, Alexandra Palmer, Valentina Massa, Alan J. Burns, Louisa P. E. Dunlevy, Sandra C. P. de Castro, Dawn Savery, Kit-Yi Leung, Andrew J. Copp, Nicholas D. E. Greene
Published 2019-11-01

Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels

by Haneesha Mohan, Monica Guzman Lenis, Evelyn Y. Laurette, Oscar Tejada, Tanvi Sanghvi, Kit-Yi Leung, Lindsay S. Cahill, John G. Sled, Paul Delgado-Olguín, Nicholas D.E. Greene, Andrew J. Copp, Lena Serghides
Published 2021-01-01

Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening

by David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
Published 2013-05-01

Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening

by David Adams, Richard Baldock, Shoumo Bhattacharya, Andrew J. Copp, Mary Dickinson, Nicholas D. E. Greene, Mark Henkelman, Monica Justice, Timothy Mohun, Stephen A. Murray, Erwin Pauws, Michael Raess, Janet Rossant, Tom Weaver, David West
Published 2013-07-01

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

by Ivan Quétier, Jacqueline J.T. Marshall, Bradley Spencer-Dene, Sylvie Lachmann, Adele Casamassima, Claudio Franco, Sarah Escuin, Joseph T. Worrall, Priththivika Baskaran, Vinothini Rajeeve, Michael Howell, Andrew J. Copp, Gordon Stamp, Ian Rosewell, Pedro Cutillas, Holger Gerhardt, Peter J. Parker, Angus J.M. Cameron
Published 2016-01-01