Molecular Subtyping and Precision Medicine for Pancreatic Cancer

by Fieke E.M. Froeling, Raffaella Casolino, Antonio Pea, Andrew V. Biankin, David K. Chang
Published 2021-01-01

Messina: a novel analysis tool to identify biologically relevant molecules in disease.

by Mark Pinese, Christopher J Scarlett, James G Kench, Emily K Colvin, Davendra Segara, Susan M Henshall, Robert L Sutherland, Andrew V Biankin
Published 2009-01-01

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs

by Billie G. C. Griffith, Rosanna Upstill-Goddard, Holly Brunton, Graeme R. Grimes, Andrew V. Biankin, Bryan Serrels, Adam Byron, Margaret C. Frame
Published 2021-01-01

Muscle-Derived Cytokines Reduce Growth, Viability and Migratory Activity of Pancreatic Cancer Cells

by Raphaela Schwappacher, Walburga Dieterich, Dejan Reljic, Christian Pilarsky, Debabrata Mukhopadhyay, David K. Chang, Andrew V. Biankin, Jürgen Siebler, Hans J. Herrmann, Markus F. Neurath, Yurdagül Zopf
Published 2021-07-01

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia.

by Andreia V Pinho, Mohammed Bensellam, Elke Wauters, Maxine Rees, Marc Giry-Laterriere, Amanda Mawson, Le Quan Ly, Andrew V Biankin, Jianmin Wu, D Ross Laybutt, Ilse Rooman
Published 2015-01-01

Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction.

by Christopher J Scarlett, Emily K Colvin, Mark Pinese, David K Chang, Adrienne L Morey, Elizabeth A Musgrove, Marina Pajic, Minoti Apte, Susan M Henshall, Robert L Sutherland, James G Kench, Andrew V Biankin
Published 2011-01-01

Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.

by Marina Pasca di Magliano, Andrew V Biankin, Patrick W Heiser, David A Cano, Pedro J A Gutierrez, Therese Deramaudt, Davendra Segara, Amanda C Dawson, James G Kench, Susan M Henshall, Robert L Sutherland, Andrzej Dlugosz, Anil K Rustgi, Matthias Hebrok
Published 2007-11-01

An unbiased high‐throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer

by Chun‐Hao Pan, Yuka Otsuka, BanuPriya Sridharan, Melissa Woo, Cindy V. Leiton, Sruthi Babu, Mariana Torrente Gonçalves, Ryan R. Kawalerski, Ji Dong K. Bai, David K. Chang, Andrew V. Biankin, Louis Scampavia, Timothy Spicer, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer
Published 2020-08-01

Retinoid signaling in pancreatic cancer, injury and regeneration.

by Emily K Colvin, Johana M Susanto, James G Kench, Vivienna N Ong, Amanda Mawson, Mark Pinese, David K Chang, Ilse Rooman, Sandra A O'Toole, Davendra Segara, Elizabeth A Musgrove, Robert L Sutherland, Minoti V Apte, Christopher J Scarlett, Andrew V Biankin
Published 2011-01-01

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

by Andreia V. Pinho, Mathias Van Bulck, Lorraine Chantrill, Mehreen Arshi, Tatyana Sklyarova, David Herrmann, Claire Vennin, David Gallego-Ortega, Amanda Mawson, Marc Giry-Laterriere, Astrid Magenau, Gunther Leuckx, Luc Baeyens, Anthony J. Gill, Phoebe Phillips, Paul Timpson, Andrew V. Biankin, Jianmin Wu, Ilse Rooman
Published 2018-11-01

SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability.

by Glenn M Marshall, Pei Y Liu, Samuele Gherardi, Christopher J Scarlett, Antonio Bedalov, Ning Xu, Nuncio Iraci, Emanuele Valli, Dora Ling, Wayne Thomas, Margo van Bekkum, Eric Sekyere, Kacper Jankowski, Toby Trahair, Karen L Mackenzie, Michelle Haber, Murray D Norris, Andrew V Biankin, Giovanni Perini, Tao Liu
Published 2011-06-01

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles.

by Sarah Song, Katia Nones, David Miller, Ivon Harliwong, Karin S Kassahn, Mark Pinese, Marina Pajic, Anthony J Gill, Amber L Johns, Matthew Anderson, Oliver Holmes, Conrad Leonard, Darrin Taylor, Scott Wood, Qinying Xu, Felicity Newell, Mark J Cowley, Jianmin Wu, Peter Wilson, Lynn Fink, Andrew V Biankin, Nic Waddell, Sean M Grimmond, John V Pearson
Published 2012-01-01

CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype

by Juliana B. Candido, Jennifer P. Morton, Peter Bailey, Andrew D. Campbell, Saadia A. Karim, Thomas Jamieson, Laura Lapienyte, Aarthi Gopinathan, William Clark, Ewan J. McGhee, Jun Wang, Monica Escorcio-Correia, Raphael Zollinger, Rozita Roshani, Lisa Drew, Loveena Rishi, Rebecca Arkell, T.R. Jeffry Evans, Colin Nixon, Duncan I. Jodrell, Robert W. Wilkinson, Andrew V. Biankin, Simon T. Barry, Frances R. Balkwill, Owen J. Sansom
Published 2018-05-01

Lost in translation: returning germline genetic results in genome-scale cancer research

by Amber L. Johns, Skye H. McKay, Jeremy L. Humphris, Mark Pinese, Lorraine A. Chantrill, R. Scott Mead, Katherine Tucker, Lesley Andrews, Annabel Goodwin, Conrad Leonard, Hilda A. High, Katia Nones, Ann-Marie Patch, Neil D. Merrett, Nick Pavlakis, Karin S. Kassahn, Jaswinder S. Samra, David K. Miller, David K. Chang, Marina Pajic, Australian Pancreatic Cancer Genome Initiative, John V. Pearson, Sean M. Grimmond, Nicola Waddell, Nikolajs Zeps, Anthony J. Gill, Andrew V. Biankin
Published 2017-04-01

Somatic point mutation calling in low cellularity tumors.

by Karin S Kassahn, Oliver Holmes, Katia Nones, Ann-Marie Patch, David K Miller, Angelika N Christ, Ivon Harliwong, Timothy J Bruxner, Qinying Xu, Matthew Anderson, Scott Wood, Conrad Leonard, Darrin Taylor, Felicity Newell, Sarah Song, Senel Idrisoglu, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, Anita Steptoe, Marina Pajic, Mark J Cowley, Mark Pinese, David K Chang, Anthony J Gill, Amber L Johns, Jianmin Wu, Peter J Wilson, Lynn Fink, Andrew V Biankin, Nicola Waddell, Sean M Grimmond, John V Pearson
Published 2013-01-01

DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association

by Vanessa Lakis, Rita T. Lawlor, Felicity Newell, Ann-Marie Patch, Andrea Mafficini, Anguraj Sadanandam, Lambros T. Koufariotis, Rebecca L. Johnston, Conrad Leonard, Scott Wood, Borislav Rusev, Vincenzo Corbo, Claudio Luchini, Sara Cingarlini, Luca Landoni, Roberto Salvia, Michele Milella, David Chang, Peter Bailey, Nigel B. Jamieson, Fraser Duthie, Marie-Claude Gingras, Donna M. Muzny, David A. Wheeler, Richard A. Gibbs, Massimo Milione, APGI, ARC-Net, Paolo Pederzoli, Jaswinder S. Samra, Anthony J. Gill, Amber L. Johns, John V. Pearson, Andrew V. Biankin, Sean M. Grimmond, Nicola Waddell, Katia Nones, Aldo Scarpa
Published 2021-02-01

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation

by Marie-Claude Gingras, Kyle R. Covington, David K. Chang, Lawrence A. Donehower, Anthony J. Gill, Michael M. Ittmann, Chad J. Creighton, Amber L. Johns, Eve Shinbrot, Ninad Dewal, William E. Fisher, Christian Pilarsky, Robert Grützmann, Michael J. Overman, Nigel B. Jamieson, George Van Buren II, Jennifer Drummond, Kimberly Walker, Oliver A. Hampton, Liu Xi, Donna M. Muzny, Harsha Doddapaneni, Sandra L. Lee, Michelle Bellair, Jianhong Hu, Yi Han, Huyen H. Dinh, Mike Dahdouli, Jaswinder S. Samra, Peter Bailey, Nicola Waddell, John V. Pearson, Ivon Harliwong, Huamin Wang, Daniela Aust, Karin A. Oien, Ralph H. Hruban, Sally E. Hodges, Amy McElhany, Charupong Saengboonmee, Fraser R. Duthie, Sean M. Grimmond, Andrew V. Biankin, David A. Wheeler, Richard A. Gibbs
Published 2016-02-01