A Drosophila model of myeloproliferative neoplasm reveals a feed-forward loop in the JAK pathway mediated by p38 MAPK signalling

by Ana Terriente-Félix, Lidia Pérez, Sarah J. Bray, Angel R. Nebreda, Marco Milán
Published 2017-04-01

Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism

by Adrián Martín-Segura, Adrián Martín-Segura, Álvaro Casadomé-Perales, Pietro Fazzari, Pietro Fazzari, José Manuel Mas, Laura Artigas, Raquel Valls, Angel R. Nebreda, Angel R. Nebreda, Carlos G. Dotti
Published 2019-06-01

Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations

by Antonija Kuzmanic, Ludovico Sutto, Giorgio Saladino, Angel R Nebreda, Francesco L Gervasio, Modesto Orozco
Published 2017-04-01

Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis

by Catrin Youssif, Monica Cubillos‐Rojas, Mònica Comalada, Elisabeth Llonch, Cristian Perna, Nabil Djouder, Angel R Nebreda
Published 2018-07-01

Age-dependent regulation of antioxidant genes by p38α MAPK in the liver

by Salvador Pérez, Sergio Rius-Pérez, Ana M. Tormos, Isabela Finamor, Ángel R. Nebreda, Raquel Taléns-Visconti, Juan Sastre
Published 2018-06-01

Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling

by Raquel Batlle, Eva Andrés, Lorena Gonzalez, Elisabet Llonch, Ana Igea, Núria Gutierrez-Prat, Antoni Berenguer-Llergo, Angel R. Nebreda
Published 2019-07-01

Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope

by Petra Mikolcevic, Michitaka Isoda, Hiroki Shibuya, Ivan del Barco Barrantes, Ana Igea, José A. Suja, Sue Shackleton, Yoshinori Watanabe, Angel R. Nebreda
Published 2016-03-01

Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α

by Ivan del Barco Barrantes, Camille Stephan-Otto Attolini, Konstantin Slobodnyuk, Ana Igea, Sara Gregorio, Sylwia Gawrzak, Roger R. Gomis, Angel R. Nebreda
Published 2018-01-01

P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim

by Ping Hu, Angel R. Nebreda, Helmut Hanenberg, Garrett H. Kinnebrew, Mircea Ivan, Mervin C. Yoder, Marie-Dominique Filippi, Hal E. Broxmeyer, Reuben Kapur
Published 2018-08-01

p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging.

by Ana M Tormos, Sergio Rius-Pérez, María Jorques, Patricia Rada, Lorena Ramirez, Ángela M Valverde, Ángel R Nebreda, Juan Sastre, Raquel Taléns-Visconti
Published 2017-01-01

Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

by Marta Navarrete, María I. Cuartero, Rocío Palenzuela, Jonathan E. Draffin, Ainoa Konomi, Irene Serra, Sandra Colié, Sergio Castaño-Castaño, Mazahir T. Hasan, Ángel R. Nebreda, José A. Esteban
Published 2019-07-01

Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population

by Jorge Gómez-Miragaya, Marta Palafox, Laia Paré, Guillermo Yoldi, Irene Ferrer, Sergi Vila, Patricia Galván, Pasquale Pellegrini, Hector Pérez-Montoyo, Ana Igea, Purificación Muñoz, Manel Esteller, Angel R. Nebreda, Ander Urruticoechea, Idoia Morilla, Sonia Pernas, Fina Climent, María Teresa Soler-Monso, Ana Petit, Violeta Serra, Aleix Prat, Eva González-Suárez
Published 2017-05-01

Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor

by Bahareh Eftekharzadeh, Varuna C. Banduseela, Giulio Chiesa, Paula Martínez-Cristóbal, Jennifer N. Rauch, Samir R. Nath, Daniel M. C. Schwarz, Hao Shao, Marta Marin-Argany, Claudio Di Sanza, Elisa Giorgetti, Zhigang Yu, Roberta Pierattelli, Isabella C. Felli, Isabelle Brun-Heath, Jesús García, Ángel R. Nebreda, Jason E. Gestwicki, Andrew P. Lieberman, Xavier Salvatella
Published 2019-08-01

Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor

by Bahareh Eftekharzadeh, Varuna C. Banduseela, Giulio Chiesa, Paula Martínez-Cristóbal, Jennifer N. Rauch, Samir R. Nath, Daniel M. C. Schwarz, Hao Shao, Marta Marin-Argany, Claudio Di Sanza, Elisa Giorgetti, Zhigang Yu, Roberta Pierattelli, Isabella C. Felli, Isabelle Brun-Heath, Jesús García, Ángel R. Nebreda, Jason E. Gestwicki, Andrew P. Lieberman, Xavier Salvatella
Published 2019-10-01

p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.

by Nuria Matesanz, Ivana Nikolic, Magdalena Leiva, Marta Pulgarín-Alfaro, Ayelén M Santamans, Edgar Bernardo, Alfonso Mora, Leticia Herrera-Melle, Elena Rodríguez, Daniel Beiroa, Ainoa Caballero, Elena Martín-García, Rebeca Acín-Pérez, Lourdes Hernández-Cosido, Luis Leiva-Vega, Jorge L Torres, Francisco Centeno, Angel R Nebreda, José Antonio Enríquez, Rubén Nogueiras, Miguel Marcos, Guadalupe Sabio
Published 2018-07-01