Preclinical development of an in vivo BCG challenge model for testing candidate TB vaccine efficacy.

by Angela M Minassian, Edward O Ronan, Hazel Poyntz, Adrian V S Hill, Helen McShane
Published 2011-01-01

Th1/Th17 cell induction and corresponding reduction in ATP consumption following vaccination with the novel Mycobacterium tuberculosis vaccine MVA85A.

by Kristin L Griffiths, Ansar A Pathan, Angela M Minassian, Clare R Sander, Natalie E R Beveridge, Adrian V S Hill, Helen A Fletcher, Helen McShane
Published 2011-01-01

Roles for Treg expansion and HMGB1 signaling through the TLR1-2-6 axis in determining the magnitude of the antigen-specific immune response to MVA85A.

by Magali Matsumiya, Elena Stylianou, Kristin Griffiths, Zoe Lang, Joel Meyer, Stephanie A Harris, Rosalind Rowland, Angela M Minassian, Ansar A Pathan, Helen Fletcher, Helen McShane
Published 2013-01-01

Tools for Assessing the Protective Efficacy of TB Vaccines in Humans: in vitro Mycobacterial Growth Inhibition Predicts Outcome of in vivo Mycobacterial Infection

by Rachel Tanner, Iman Satti, Stephanie A. Harris, Matthew K. O'Shea, Matthew K. O'Shea, Deniz Cizmeci, Daniel O'Connor, Agnieszka Chomka, Magali Matsumiya, Rachel Wittenberg, Angela M. Minassian, Joel Meyer, Helen A. Fletcher, Helen A. Fletcher, Helen McShane
Published 2020-01-01

Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum

by Kathryn Milne, Alasdair Ivens, Adam J Reid, Magda E Lotkowska, Aine O'Toole, Geetha Sankaranarayanan, Diana Munoz Sandoval, Wiebke Nahrendorf, Clement Regnault, Nick J Edwards, Sarah E Silk, Ruth O Payne, Angela M Minassian, Navin Venkatraman, Mandy J Sanders, Adrian VS Hill, Michael Barrett, Matthew Berriman, Simon J Draper, J Alexandra Rowe, Philip J Spence
Published 2021-03-01

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools

by Anne S. De Groot, Anne S. De Groot, Leonard Moise, Leonard Moise, Frances Terry, Andres H. Gutierrez, Andres H. Gutierrez, Pooja Hindocha, Guilhem Richard, Daniel Fredric Hoft, Ted M. Ross, Amy R. Noe, Yoshimasa Takahashi, Vinayaka Kotraiah, Sarah E. Silk, Carolyn M. Nielsen, Angela M. Minassian, Rebecca Ashfield, Matt Ardito, Simon J. Draper, William D. Martin
Published 2020-04-01

Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial

by Hans de Graaf, Ruth O. Payne, Iona Taylor, Kazutoyo Miura, Carol A. Long, Sean C. Elias, Marija Zaric, Angela M. Minassian, Sarah E. Silk, Lee Li, Ian D. Poulton, Megan Baker, Simon J. Draper, Diane Gbesemete, Nathan J. Brendish, Filipa Martins, Arianna Marini, David Mekhaiel, Nick J. Edwards, Rachel Roberts, Johan Vekemans, Sarah Moyle, Saul N. Faust, Eleanor Berrie, Alison M. Lawrie, Fergal Hill, Adrian V. S. Hill, Sumi Biswas
Published 2021-07-01