Pathways Responsible for Human Autoantibody and Therapeutic Intravenous IgG Activity in Humanized Mice

by Inessa Schwab, Anja Lux, Falk Nimmerjahn
Published 2015-10-01

The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity

by Sina Gordan, Heike Albert, Heike Danzer, Anja Lux, Markus Biburger, Falk Nimmerjahn
Published 2019-12-01

Impact of Plasma Membrane Domains on IgG Fc Receptor Function

by Sibel Kara, Lukas Amon, Jennifer J. Lühr, Jennifer J. Lühr, Falk Nimmerjahn, Falk Nimmerjahn, Falk Nimmerjahn, Diana Dudziak, Diana Dudziak, Diana Dudziak, Diana Dudziak, Anja Lux, Anja Lux
Published 2020-06-01

A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors

by Daniela Kao, Heike Danzer, Mattias Collin, Andrea Groß, Jutta Eichler, Jerko Stambuk, Gordan Lauc, Anja Lux, Falk Nimmerjahn
Published 2015-12-01

Expression Profiling and Glycan Engineering of IgG Subclass 1–4 in Nicotiana benthamiana

by Somanath Kallolimath, Thomas Hackl, Raphaela Gahn, Clemens Grünwald-Gruber, Wilhelm Zich, Benjamin Kogelmann, Anja Lux, Falk Nimmerjahn, Herta Steinkellner
Published 2020-07-01

Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis

by Heike Danzer, Joachim Glaesner, Anne Baerenwaldt, Carmen Reitinger, Anja Lux, Lukas Heger, Diana Dudziak, Thomas Harrer, André Gessner, Falk Nimmerjahn
Published 2020-07-01

Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength

by Sina Bondza, Sina Bondza, Anita Marosan, Sibel Kara, Josephine Lösing, Matthias Peipp, Falk Nimmerjahn, Jos Buijs, Jos Buijs, Anja Lux
Published 2021-01-01

Targeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology

by Anja Werner, Simon Schäfer, Olga Zaytseva, Heike Albert, Anja Lux, Jasminka Krištić, Marija Pezer, Gordan Lauc, Thomas Winkler, Falk Nimmerjahn
Published 2021-09-01

A Humanized Mouse Identifies the Bone Marrow as a Niche with Low Therapeutic IgG Activity

by Anja Lux, Michaela Seeling, Anne Baerenwaldt, Birgit Lehmann, Inessa Schwab, Roland Repp, Norbert Meidenbauer, Andreas Mackensen, Arndt Hartmann, Gordon Heidkamp, Diana Dudziak, Falk Nimmerjahn
Published 2014-04-01

Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo

by Anja Schaffert, Maja Hanić, Mislav Novokmet, Olga Zaytseva, Jasminka Krištić, Anja Lux, Lars Nitschke, Matthias Peipp, Marija Pezer, René Hennig, René Hennig, Erdmann Rapp, Erdmann Rapp, Gordan Lauc, Gordan Lauc, Falk Nimmerjahn
Published 2020-01-01