Pichia pastoris-Expressed Bivalent Virus-Like Particulate Vaccine Induces Domain III-Focused Bivalent Neutralizing Antibodies without Antibody-Dependent Enhancement in Vivo

by Rahul Shukla, Ravi K. Rajpoot, Upasana Arora, Ankur Poddar, Sathyamangalam Swaminathan, Navin Khanna, Navin Khanna, Navin Khanna
Published 2018-01-01

Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models

by Rahul Shukla, Hemalatha Beesetti, Julia A. Brown, Richa Ahuja, Viswanathan Ramasamy, Rajgokul K. Shanmugam, Ankur Poddar, Gaurav Batra, Florian Krammer, Jean K. Lim, Sachin Kale, Altaf A. Lal, Sathyamangalam Swaminathan, Navin Khanna
Published 2020-10-01

A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confe...

by Viswanathan Ramasamy, Upasana Arora, Rahul Shukla, Ankur Poddar, Rajgokul K Shanmugam, Laura J White, Melissa M Mattocks, Rajendra Raut, Ashiya Perween, Poornima Tyagi, Aravinda M de Silva, Siddhartha K Bhaumik, Murali Krishna Kaja, François Villinger, Rafi Ahmed, Robert E Johnston, Sathyamangalam Swaminathan, Navin Khanna
Published 2018-01-01