Unexpectedly Higher Morbidity and Mortality of Hospitalized Elderly Patients Associated with Rhinovirus Compared with Influenza Virus Respiratory Tract Infection

by Ivan F. N. Hung, Anna Jinxia Zhang, Kelvin K. W. To, Jasper F. W. Chan, Shawn H. S. Zhu, Ricky Zhang, Tuen-Ching Chan, Kwok-Hung Chan, Kwok-Yung Yuen
Published 2017-01-01

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges

by Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Can Li, Yanxia Chen, Feifei Liu, Yan Zhao, Hin Chu, Carol Ho-Yan Fong, Pui Wang, Siu-Ying Lau, Kelvin Kai-Wang To, Honglin Chen, Kwok-Yung Yuen
Published 2021-08-01

Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine

by Lu Lu, Carol Ho-Yan Fong, Anna Jinxia Zhang, Wai-Lan Wu, Iris Can Li, Andrew Chak-Yiu Lee, Thrimendra Kaushika Dissanayake, Linlei Chen, Ivan Fan-Ngai Hung, Kwok-Hung Chan, Hin Chu, Kin-Hang Kok, Kwok-Yung Yuen, Kelvin Kai-Wang To
Published 2020-12-01

Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2

by Hanjun Zhao, Kelvin K. W. To, Hoiyan Lam, Xinxin Zhou, Jasper Fuk-Woo Chan, Zheng Peng, Andrew C. Y. Lee, Jianpiao Cai, Wan-Mui Chan, Jonathan Daniel Ip, Chris Chung-Sing Chan, Man Lung Yeung, Anna Jinxia Zhang, Allen Wing Ho Chu, Shibo Jiang, Kwok-Yung Yuen
Published 2021-03-01

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

by Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Jasper Fuk-Woo Chan, Can Li, Zhimeng Fan, Feifei Liu, Yanxia Chen, Ronghui Liang, Siddharth Sridhar, Jian-Piao Cai, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Kelvin Kai-Wang To, Shuofeng Yuan, Jie Zhou, Hin Chu, Kwok-Yung Yuen
Published 2020-10-01

Characterization of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike protein

by Pui Wang, Siu-Ying Lau, Shaofeng Deng, Pin Chen, Bobo Wing-Yee Mok, Anna Jinxia Zhang, Andrew Chak-Yiu Lee, Kwok-Hung Chan, Rachel Chun-Yee Tam, Haoran Xu, Runhong Zhou, Wenjun Song, Li Liu, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Zhiwei Chen, Kwok-Yung Yuen, Honglin Chen
Published 2021-05-01

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

by Bobo Wing-Yee Mok, Honglian Liu, Shaofeng Deng, Jiayan Liu, Anna Jinxia Zhang, Siu-Ying Lau, Siwen Liu, Rachel Chun-Yee Tam, Conor J. Cremin, Timothy Ting-Leung Ng, Jake Siu-Lun Leung, Lam-Kwong Lee, Pui Wang, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Hung Chan, Kwok-Yung Yuen, Gilman Kit-Hang Siu, Honglin Chen
Published 2021-09-01

SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of...

by Hin Chu, Jasper Fuk-Woo Chan, Yixin Wang, Terrence Tsz-Tai Yuen, Yue Chai, Huiping Shuai, Dong Yang, Bingjie Hu, Xiner Huang, Xi Zhang, Yuxin Hou, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Kelvin Kai-Wang To, Ivan Fan-Ngai Hung, Tan To Cheung, Ada Tsui-Lin Ng, Ivy Hau-Yee Chan, Ian Yu-Hong Wong, Simon Ying-Kit Law, Dominic Chi-Chung Foo, Wai-Keung Leung, Kwok-Yung Yuen
Published 2021-01-01

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

by Hin Chu, Bingjie Hu, Xiner Huang, Yue Chai, Dongyan Zhou, Yixin Wang, Huiping Shuai, Dong Yang, Yuxin Hou, Xi Zhang, Terrence Tsz-Tai Yuen, Jian-Piao Cai, Anna Jinxia Zhang, Jie Zhou, Shuofeng Yuan, Kelvin Kai-Wang To, Ivy Hau-Yee Chan, Ko-Yung Sit, Dominic Chi-Chung Foo, Ian Yu-Hong Wong, Ada Tsui-Lin Ng, Tan To Cheung, Simon Ying-Kit Law, Wing-Kuk Au, Melinda A. Brindley, Zhiwei Chen, Kin-Hang Kok, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
Published 2021-01-01