SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site

by Anna Z Mykytyn, Tim I Breugem, Samra Riesebosch, Debby Schipper, Petra B van den Doel, Robbert J Rottier, Mart M Lamers, Bart L Haagmans
Published 2021-01-01

Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

by Mart M Lamers, Anna Z Mykytyn, Tim I Breugem, Yiquan Wang, Douglas C Wu, Samra Riesebosch, Petra B van den Doel, Debby Schipper, Theo Bestebroer, Nicholas C Wu, Bart L Haagmans
Published 2021-04-01

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

by Joep Beumer, Maarten H. Geurts, Mart M. Lamers, Jens Puschhof, Jingshu Zhang, Jelte van der Vaart, Anna Z. Mykytyn, Tim I. Breugem, Samra Riesebosch, Debby Schipper, Petra B. van den Doel, Wim de Lau, Cayetano Pleguezuelos-Manzano, Georg Busslinger, Bart L. Haagmans, Hans Clevers
Published 2021-09-01