pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study

by Angélique Stéphanou, Annabelle Ballesta
Published 2019-02-01

A mathematical model of the circadian clock and drug pharmacology to optimize irinotecan administration timing in colorectal cancer

by Janina Hesse, Julien Martinelli, Ouda Aboumanify, Annabelle Ballesta, Angela Relógio
Published 2021-01-01

Optimizing circadian drug infusion schedules towards personalized cancer chronotherapy.

by Roger J W Hill, Pasquale F Innominato, Francis Lévi, Annabelle Ballesta
Published 2020-01-01

Data-driven modeling of SRC control on the mitochondrial pathway of apoptosis: implication for anticancer therapy optimization.

by Annabelle Ballesta, Jonathan Lopez, Nikolay Popgeorgiev, Philippe Gonzalo, Marie Doumic, Germain Gillet
Published 2013-04-01

A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery.

by Annabelle Ballesta, Sandrine Dulong, Chadi Abbara, Boris Cohen, Alper Okyar, Jean Clairambault, Francis Levi
Published 2011-09-01

An efficient kinetic model for assemblies of amyloid fibrils and its application to polyglutamine aggregation.

by Stéphanie Prigent, Annabelle Ballesta, Frédérique Charles, Natacha Lenuzza, Pierre Gabriel, Léon Matar Tine, Human Rezaei, Marie Doumic
Published 2012-01-01

Sex‐dependent least toxic timing of irinotecan combined with chronomodulated chemotherapy for metastatic colorectal cancer: Randomized multicenter EORTC 05011 trial

by Pasquale F. Innominato, Annabelle Ballesta, Qi Huang, Christian Focan, Philippe Chollet, Abdoulaye Karaboué, Sylvie Giacchetti, Mohamed Bouchahda, René Adam, Carlo Garufi, Francis A. Lévi
Published 2020-06-01

BMAL1 Knockdown Leans Epithelial–Mesenchymal Balance toward Epithelial Properties and Decreases the Chemoresistance of Colon Carcinoma Cells

by Yuan Zhang, Aurore Devocelle, Christophe Desterke, Lucas Eduardo Botelho de Souza, Éva Hadadi, Hervé Acloque, Adlen Foudi, Yao Xiang, Annabelle Ballesta, Yunhua Chang, Julien Giron-Michel
Published 2021-05-01

Circadian rest‐activity rhythm as an objective biomarker of patient‐reported outcomes in patients with advanced cancer

by Pasquale F. Innominato, Sandra Komarzynski, Oxana G. Palesh, Robert Dallmann, Georg A. Bjarnason, Sylvie Giacchetti, Ayhan Ulusakarya, Mohamed Bouchahda, Mazen Haydar, Annabelle Ballesta, Abdoulaye Karaboué, Nicholas I. Wreglesworth, David Spiegel, Francis A. Lévi
Published 2018-09-01