Nitrosative stress and redox-cycling agents synergize to cause mitochondrial dysfunction and cell death in endothelial cells

by Anne R. Diers, Katarzyna A. Broniowska, Neil Hogg
Published 2013-01-01

Oxidative modification of proteins: An emerging mechanism of cell signaling

by Stephanie B. Wall, Joo-Yeun eOh, Anne R. Diers, Aimee eLandar
Published 2012-09-01

Mitochondrial bioenergetics of metastatic breast cancer cells in response to dynamic changes in oxygen tension: effects of HIF-1α.

by Anne R Diers, Praveen K Vayalil, Claudia R Oliva, Corinne E Griguer, Victor Darley-Usmar, Douglas R Hurst, Danny R Welch, Aimee Landar
Published 2013-01-01

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.

by Praveen K Vayalil, Joo-Yeun Oh, Fen Zhou, Anne R Diers, M Ryan Smith, Hafez Golzarian, Patsy G Oliver, Robin A J Smith, Michael P Murphy, Sadanandan E Velu, Aimee Landar
Published 2015-01-01

High levels of ubidecarenone (oxidized CoQ10) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma ver...

by Jiaxin Sun, Chirag B. Patel, Taichang Jang, Milton Merchant, Chen Chen, Shiva Kazerounian, Anne R. Diers, Michael A. Kiebish, Vivek K. Vishnudas, Stephane Gesta, Rangaprasad Sarangarajan, Niven R. Narain, Seema Nagpal, Lawrence Recht
Published 2020-08-01

Elevated levels of mitochondrial CoQ10 induce ROS-mediated apoptosis in pancreatic cancer

by Tulin Dadali, Anne R. Diers, Shiva Kazerounian, Senthil K. Muthuswamy, Pallavi Awate, Ryan Ng, Saie Mogre, Carrie Spencer, Katerina Krumova, Hannah E. Rockwell, Justice McDaniel, Emily Y. Chen, Fei Gao, Karl T. Diedrich, Vijetha Vemulapalli, Leonardo O. Rodrigues, Viatcheslav R. Akmaev, Khampaseuth Thapa, Manuel Hidalgo, Arindam Bose, Vivek K. Vishnudas, A. James Moser, Elder Granger, Michael A. Kiebish, Stephane Gesta, Niven R. Narain, Rangaprasad Sarangarajan
Published 2021-03-01