Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network

by Simona Gribaudo, Philippe Tixador, Luc Bousset, Alexis Fenyi, Patricia Lino, Ronald Melki, Jean-Michel Peyrin, Anselme L. Perrier
Published 2019-02-01

Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells.

by Carla Lopes, Sophie Aubert, Fany Bourgois-Rocha, Monia Barnat, Ana Cristina Rego, Nicole Déglon, Anselme L Perrier, Sandrine Humbert
Published 2016-01-01

Differentiation of nonhuman primate pluripotent stem cells into functional keratinocytes

by Sophie Domingues, Yolande Masson, Aurore Marteyn, Jennifer Allouche, Anselme L. Perrier, Marc Peschanski, Cecile Martinat, Christine Baldeschi, Gilles Lemaître
Published 2017-12-01

CTIP2-Regulated Reduction in PKA-Dependent DARPP32 Phosphorylation in Human Medium Spiny Neurons: Implications for Huntington Disease

by Marija Fjodorova, Morgane Louessard, Zongze Li, Daniel C. De La Fuente, Emma Dyke, Simon P. Brooks, Anselme L. Perrier, Meng Li
Published 2019-09-01

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

by Romina Aron Badin, Aurore Bugi, Susannah Williams, Marta Vadori, Marie Michael, Caroline Jan, Alberto Nassi, Sophie Lecourtois, Antoine Blancher, Emanuele Cozzi, Philippe Hantraye, Anselme L. Perrier
Published 2019-09-01

Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing

by Karine Cambon, Virginie Zimmer, Sylvain Martineau, Marie-Claude Gaillard, Margot Jarrige, Aurore Bugi, Jana Miniarikova, Maria Rey, Raymonde Hassig, Noelle Dufour, Gwenaelle Auregan, Philippe Hantraye, Anselme L. Perrier, Nicole Déglon
Published 2017-06-01

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines

by Sylvain Perriot, Amandine Mathias, Guillaume Perriard, Mathieu Canales, Nils Jonkmans, Nicolas Merienne, Cécile Meunier, Lina El Kassar, Anselme L. Perrier, David-Axel Laplaud, Myriam Schluep, Nicole Déglon, Renaud Du Pasquier
Published 2018-11-01

Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates

by Sonia Lavisse, Susannah Williams, Sophie Lecourtois, Nadja van Camp, Martine Guillermier, Pauline Gipchtein, Caroline Jan, Sébastien Goutal, Leopold Eymin, Julien Valette, Thierry Delzescaux, Anselme L. Perrier, Philippe Hantraye, Romina Aron Badin
Published 2019-10-01

Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells.

by Valérie Drouet, Marta Ruiz, Diana Zala, Maxime Feyeux, Gwennaëlle Auregan, Karine Cambon, Laetitia Troquier, Johann Carpentier, Sophie Aubert, Nicolas Merienne, Fany Bourgois-Rocha, Raymonde Hassig, Maria Rey, Noëlle Dufour, Frédéric Saudou, Anselme L Perrier, Philippe Hantraye, Nicole Déglon
Published 2014-01-01

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes

by Nicolas Merienne, Gabriel Vachey, Lucie de Longprez, Cécile Meunier, Virginie Zimmer, Guillaume Perriard, Mathieu Canales, Amandine Mathias, Lucas Herrgott, Tim Beltraminelli, Axelle Maulet, Thomas Dequesne, Catherine Pythoud, Maria Rey, Luc Pellerin, Emmanuel Brouillet, Anselme L. Perrier, Renaud du Pasquier, Nicole Déglon
Published 2017-09-01