Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells

by Victoria Fernández-García, Victoria Fernández-García, Silvia González-Ramos, Silvia González-Ramos, Paloma Martín-Sanz, Paloma Martín-Sanz, Antonio Castrillo, Antonio Castrillo, Antonio Castrillo, Lisardo Boscá, Lisardo Boscá, Lisardo Boscá
Published 2020-10-01

The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages

by Concha Nieto, Rafael Bragado, Cristina Municio, Elena Sierra-Filardi, Bárbara Alonso, María M. Escribese, Jorge Domínguez-Andrés, Carlos Ardavín, Antonio Castrillo, Antonio Castrillo, Miguel A. Vega, Amaya Puig-Kröger, Angel L. Corbí
Published 2018-01-01

Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP

by Li Zhang, Prashant Rajbhandari, Christina Priest, Jaspreet Sandhu, Xiaohui Wu, Ryan Temel, Antonio Castrillo, Thomas Q de Aguiar Vallim, Tamer Sallam, Peter Tontonoz
Published 2017-10-01

Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory Pathways in Macrophages

by Cristina M. Ramírez, Marta Torrecilla-Parra, Virginia Pardo-Marqués, Mario Fernández de-Frutos, Ana Pérez-García, Carlos Tabraue, Carlos Tabraue, Juan Vladimir de la Rosa, Patricia Martín-Rodriguez, Mercedes Díaz-Sarmiento, Uxue Nuñez, Marta C. Orizaola, Paqui G. Través, Marta Camps, Lisardo Boscá, Lisardo Boscá, Lisardo Boscá, Antonio Castrillo, Antonio Castrillo
Published 2021-05-01

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism

by Jonathan Matalonga, Estibaliz Glaria, Mariana Bresque, Carlos Escande, José María Carbó, Kerstin Kiefer, Ruben Vicente, Theresa E. León, Susana Beceiro, Mónica Pascual-García, Joan Serret, Lucía Sanjurjo, Samantha Morón-Ros, Antoni Riera, Sonia Paytubi, Antonio Juarez, Fernando Sotillo, Lennart Lindbom, Carme Caelles, Maria-Rosa Sarrias, Jaime Sancho, Antonio Castrillo, Eduardo N. Chini, Annabel F. Valledor
Published 2017-01-01