The 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease

by Sophie R. Robinson, Antony W. Oliver, Timothy J. Chevassut, Sarah F. Newbury
Published 2015-07-01

BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands

by Matthew Day, Mathieu Rappas, Katie Ptasinska, Dominik Boos, Antony W Oliver, Laurence H Pearl
Published 2018-10-01

A role of the Nse4 kleisin and Nse1/Nse3 KITE subunits in the ATPase cycle of SMC5/6

by Lucie Vondrova, Peter Kolesar, Marek Adamus, Matej Nociar, Antony W. Oliver, Jan J. Palecek
Published 2020-06-01

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

by Nicolas Bigot, Matthew Day, Robert A Baldock, Felicity Z Watts, Antony W Oliver, Laurence H Pearl
Published 2019-05-01

PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.

by Nadia Hégarat, Clare Vesely, P K Vinod, Cory Ocasio, Nisha Peter, Julian Gannon, Antony W Oliver, Béla Novák, Helfrid Hochegger
Published 2014-01-01

The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins

by Gabrielle J. Grundy, Stuart L. Rulten, Raquel Arribas-Bosacoma, Kathryn Davidson, Zuzanna Kozik, Antony W. Oliver, Laurence H. Pearl, Keith W. Caldecott
Published 2016-04-01

ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX

by Robert A. Baldock, Matthew Day, Oliver J. Wilkinson, Ross Cloney, Penelope A. Jeggo, Antony W. Oliver, Felicity Z. Watts, Laurence H. Pearl
Published 2015-12-01

Inhibition of MRN activity by a telomere protein motif

by Freddy Khayat, Elda Cannavo, Majedh Alshmery, William R. Foster, Charly Chahwan, Martino Maddalena, Christopher Smith, Antony W. Oliver, Adam T. Watson, Antony M. Carr, Petr Cejka, Alessandro Bianchi
Published 2021-06-01

Live-cell single-molecule tracking highlights requirements for stable Smc5/6 chromatin association in vivo

by Thomas J Etheridge, Desiree Villahermosa, Eduard Campillo-Funollet, Alex David Herbert, Anja Irmisch, Adam T Watson, Hung Q Dang, Mark A Osborne, Antony W Oliver, Antony M Carr, Johanne M Murray
Published 2021-04-01

Specialized interfaces of Smc5/6 control hinge stability and DNA association

by Aaron Alt, Hung Q. Dang, Owen S. Wells, Luis M. Polo, Matt A. Smith, Grant A. McGregor, Thomas Welte, Alan R. Lehmann, Laurence H. Pearl, Johanne M. Murray, Antony W. Oliver
Published 2017-01-01

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity

by Jordan R. Becker, Raquel Cuella-Martin, Marco Barazas, Rui Liu, Catarina Oliveira, Antony W. Oliver, Kirstin Bilham, Abbey B. Holt, Andrew N. Blackford, Jörg Heierhorst, Jos Jonkers, Sven Rottenberg, J. Ross Chapman
Published 2018-12-01

PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2

by Gabrielle J. Grundy, Luis M. Polo, Zhihong Zeng, Stuart L. Rulten, Nicolas C. Hoch, Pathompong Paomephan, Yingqi Xu, Steve M. Sweet, Alan W. Thorne, Antony W. Oliver, Steve J. Matthews, Laurence H. Pearl, Keith W. Caldecott
Published 2016-08-01

A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development.

by Philip J Byrd, Grant S Stewart, Anna Smith, Charlotte Eaton, Alexander J Taylor, Chloe Guy, Ieva Eringyte, Peggy Fooks, James I Last, Robert Horsley, Antony W Oliver, Dragana Janic, Lidija Dokmanovic, Tatjana Stankovic, A Malcolm R Taylor
Published 2016-03-01

Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein

by Xiangrong Chen, Yusuf I Ali, Charlotte EL Fisher, Raquel Arribas-Bosacoma, Mohan B Rajasekaran, Gareth Williams, Sarah Walker, Jessica R Booth, Jessica JR Hudson, S Mark Roe, Laurence H Pearl, Simon E Ward, Frances MG Pearl, Antony W Oliver
Published 2021-03-01

Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2.

by M Cris Silva-Santisteban, Isaac M Westwood, Kathy Boxall, Nathan Brown, Sam Peacock, Craig McAndrew, Elaine Barrie, Meirion Richards, Amin Mirza, Antony W Oliver, Rosemary Burke, Swen Hoelder, Keith Jones, G Wynne Aherne, Julian Blagg, Ian Collins, Michelle D Garrett, Rob L M van Montfort
Published 2013-01-01