M48U1 CD4 mimetic has a sustained inhibitory effect on cell-associated HIV-1 by attenuating virion infectivity through gp120 shedding

by Selhorst Philippe, Grupping Katrijn, Tong Tommy, Crooks Ema T, Martin Loïc, Vanham Guido, Binley James M, Ariën Kevin K
Published 2013-02-01

MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency

by Grupping Katrijn, Selhorst Philippe, Michiels Johan, Vereecken Katleen, Heyndrickx Leo, Kessler Pascal, Vanham Guido, Martin Loïc, Ariën Kevin K
Published 2012-05-01

The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness

by Butel Christelle, Vidal Nicole, Jennes Wim, Clybergh Claude, Vanham Guido, Gali Youssef, Njai Harr F, Mpoudi-Ngolle Eitel, Peeters Martine, Ariën Kevin K
Published 2006-07-01

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

by Meuwissen Pieter J, Stolp Bettina, Iannucci Veronica, Vermeire Jolien, Naessens Evelien, Saksela Kalle, Geyer Matthias, Vanham Guido, Arien Kevin K, Fackler Oliver T, Verhasselt Bruno
Published 2012-04-01

Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness

by Vanham Guido, Zorgdrager Fokla, Dekker Stefan J, Gali Youssef, Balázs Victoria R, Ariën Kevin K, Kozaczynska Karolina, van der Kuyl Antoinette C, Berkhout Ben, Cornelissen Marion
Published 2010-07-01

Development of triazine non-nucleoside reverse transcriptase inhibitors for microbicidal applications

by Lewi Paul, Crucitti Tania, Cuylaerts Vicky, Abdellati Said, Heeres Jan, der Veken PieterVan, Joossens Jurgen, Míchiels Johan, Venkatraj Muthusamy, Ariën Kevin K, Augustyns Koen, Vanham Guido
Published 2011-10-01