mTOR Pathways in Cancer and Autophagy

by Mathieu Paquette, Leeanna El-Houjeiri, Arnim Pause
Published 2018-01-01

Folliculin: A Regulator of Transcription Through AMPK and mTOR Signaling Pathways

by Josué M. J. Ramirez Reyes, Josué M. J. Ramirez Reyes, Rafael Cuesta, Rafael Cuesta, Arnim Pause, Arnim Pause
Published 2021-04-01

HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.

by Marie-Claude Gingras, Yu Ling Zhang, Dmitri Kharitidi, Alastair J Barr, Stefan Knapp, Michel L Tremblay, Arnim Pause
Published 2009-01-01

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration

by Dmitri Kharitidi, Pirjo M. Apaja, Sanaz Manteghi, Kei Suzuki, Elena Malitskaya, Ariel Roldan, Marie-Claude Gingras, Junichi Takagi, Gergely L. Lukacs, Arnim Pause
Published 2015-10-01

Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer

by Sanaz Manteghi, Marie-Claude Gingras, Dmitri Kharitidi, Luc Galarneau, Maud Marques, Ming Yan, Regina Cencic, Francis Robert, Marilène Paquet, Michael Witcher, Jerry Pelletier, Arnim Pause
Published 2016-05-01

The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance

by Leeanna El-Houjeiri, Elite Possik, Tarika Vijayaraghavan, Mathieu Paquette, José A. Martina, Jalal M. Kazan, Eric H. Ma, Russell Jones, Paola Blanchette, Rosa Puertollano, Arnim Pause
Published 2019-03-01

AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

by Rebecca C. Rabinovitch, Bozena Samborska, Brandon Faubert, Eric H. Ma, Simon-Pierre Gravel, Sylvia Andrzejewski, Thomas C. Raissi, Arnim Pause, Julie St.-Pierre, Russell G. Jones
Published 2017-10-01

FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores.

by Elite Possik, Andrew Ajisebutu, Sanaz Manteghi, Marie-Claude Gingras, Tarika Vijayaraghavan, Mathieu Flamand, Barry Coull, Kathrin Schmeisser, Thomas Duchaine, Maurice van Steensel, David H Hall, Arnim Pause
Published 2015-10-01

Folliculin regulates ampk-dependent autophagy and metabolic stress survival.

by Elite Possik, Zahra Jalali, Yann Nouët, Ming Yan, Marie-Claude Gingras, Kathrin Schmeisser, Lorena Panaite, Fanny Dupuy, Dmitri Kharitidi, Laëtitia Chotard, Russell G Jones, David H Hall, Arnim Pause
Published 2014-04-01

The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting

by Derek T Hall, Takla Griss, Jennifer F Ma, Brenda Janice Sanchez, Jason Sadek, Anne Marie K Tremblay, Souad Mubaid, Amr Omer, Rebecca J Ford, Nathalie Bedard, Arnim Pause, Simon S Wing, Sergio Di Marco, Gregory R Steinberg, Russell G Jones, Imed‐Eddine Gallouzi
Published 2018-07-01

Investigating the effects of the von Hippel Lindau tumor suppressor on extracellular matrix function

by Panneton, Vanessa
Published 2011

Characterizing the novel GTPase function of folliculin and its role in tumorigenesis

by Latapie, Sebastien
Published 2012

Identifying the novel GTPase function of FLCN and characterizing its role in aging

by Ghazi, Abbas
Published 2011

Investigating tumor suppressor genes involved in renal cell carcinomas

by Hudon, Valerie
Published 2010

Characterization of a novel role of the Birt-Hogg-Dubé tumor suppressor protein in metabolism

by Sabourin, Sylvie
Published 2010

Functional characterisation of the hepatitis C virus NS2/3 and NS2 proteins

by Welbourn, Sarah
Published 2010

Characterization of novel anti-EGFR single domain antibodies and their application in active targeting of superparamagnetic iron oxide nanoparticles to glioblastoma

by Trojahn, Ulrike
Published 2012