Inhibition and Biochemical Characterization of Methicillin-Resistant Staphylococcus aureus Shikimate Dehydrogenase: An in Silico and Kinetic Study

by Claudia Avitia-Domínguez, Erick Sierra-Campos, José Manuel Salas-Pacheco, Hugo Nájera, Arturo Rojo-Domínguez, Jorge Cisneros-Martínez, Alfredo Téllez-Valencia
Published 2014-04-01

Engineering and Directed Evolution of a Ca2+ Binding Site A-Deficient AprE Mutant Reveal an Essential Contribution of the Loop Leu75–Leu82 to Enzyme Activity

by Eliel R. Romero-García, Alfredo Téllez-Valencia, María F. Trujillo, José G. Sampedro, Hugo Nájera, Arturo Rojo-Domínguez, Jesús García-Soto, Mario Pedraza-Reyes
Published 2009-01-01

The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivo

by Pedro Cruz-Nova, Michael Schnoor, José Correa-Basurto, Martiniano Bello, Paola Briseño-Diaz, Arturo Rojo-Domínguez, Carlos M. Ortiz-Mendoza, Jorge Guerrero-Aguirre, Francisco J. García-Vázquez, Rosaura Hernández-Rivas, María del Rocío Thompson-Bonilla, Miguel Vargas
Published 2018-11-01

Laccases: structure, function, and potential application in water bioremediation

by Leticia Arregui, Marcela Ayala, Ximena Gómez-Gil, Guadalupe Gutiérrez-Soto, Carlos Eduardo Hernández-Luna, Mayra Herrera de los Santos, Laura Levin, Arturo Rojo-Domínguez, Daniel Romero-Martínez, Mario C. N. Saparrat, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz
Published 2019-11-01

KRas4B-PDE6δ complex stabilization by small molecules obtained by virtual screening affects Ras signaling in pancreatic cancer

by Diana Casique-Aguirre, Paola Briseño-Díaz, Ponciano García-Gutiérrez, Claudia Haydée González-de la Rosa, Reyna Sara Quintero-Barceinas, Arturo Rojo-Domínguez, Irene Vergara, Luis Alberto Medina, José Correa-Basurto, Martiniano Bello, Rosaura Hernández-Rivas, María del RocioThompson-Bonilla, Miguel Vargas
Published 2018-12-01