An Update on the Metabolic Roles of Carbonic Anhydrases in the Model Alga Chlamydomonas reinhardtii

by Ashok Aspatwar, Susanna Haapanen, Seppo Parkkila
Published 2018-03-01

An update on anticancer drug development and delivery targeting carbonic anhydrase IX

by Justina Kazokaitė, Ashok Aspatwar, Seppo Parkkila, Daumantas Matulis
Published 2017-11-01

Cytokine profile and nitric oxide levels in peritoneal macrophages of BALB/c mice exposed to the fucose-mannose ligand of Leishmania infantum combined with glycyrrhizin

by Hasan Namdar Ahmadabad, Reza Shafiei, Gholam Reza Hatam, Reza Zolfaghari Emameh, Ashok Aspatwar
Published 2020-07-01

Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

by Ashok Aspatwar, Emanuela Berrino, Silvia Bua, Fabrizio Carta, Clemente Capasso, Seppo Parkkila, Claudiu T. Supuran
Published 2020-01-01

Carbonic anhydrase related protein expression in astrocytomas and oligodendroglial tumors

by Sini L. Karjalainen, Hannu K. Haapasalo, Ashok Aspatwar, Harlan Barker, Seppo Parkkila, Joonas A. Haapasalo
Published 2018-05-01

Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on <i>In Vitro</i> and <i>In Vivo</i> Studies

by Ashok Aspatwar, Jean-Yves Winum, Fabrizio Carta, Claudiu T. Supuran, Milka Hammaren, Mataleena Parikka, Seppo Parkkila
Published 2018-11-01

In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos

by Ashok Aspatwar, Milka Hammaren, Mataleena Parikka, Seppo Parkkila, Fabrizio Carta, Murat Bozdag, Daniela Vullo, Claudiu T. Supuran
Published 2020-01-01

<i>Mycobacterium tuberculosis</i> <i>β</i>-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs

by Ashok Aspatwar, Visvaldas Kairys, Sangeetha Rala, Mataleena Parikka, Murat Bozdag, Fabrizio Carta, Claudiu T. Supuran, Seppo Parkkila
Published 2019-10-01

β-CA-specific inhibitor dithiocarbamate Fc14–584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis

by Ashok Aspatwar, Milka Hammarén, Sanni Koskinen, Bruno Luukinen, Harlan Barker, Fabrizio Carta, Claudiu T. Supuran, Mataleena Parikka, Seppo Parkkila
Published 2017-01-01

Zebrafish as a Model Organism for the Development of Drugs for Skin Cancer

by Fatemeh Bootorabi, Hamed Manouchehri, Reza Changizi, Harlan Barker, Elisabetta Palazzo, Annalisa Saltari, Mataleena Parikka, Carlo Pincelli, Ashok Aspatwar
Published 2017-07-01

Catalytically inactive carbonic anhydrase‐related proteins enhance transport of lactate by MCT1

by Ashok Aspatwar, Martti E. E. Tolvanen, Hans‐Peter Schneider, Holger M. Becker, Susanna Narkilahti, Seppo Parkkila, Joachim W. Deitmer
Published 2019-07-01

Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series

by Ashok Aspatwar, Nanda Kumar Parvathaneni, Harlan Barker, Emilie Anduran, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Seppo Parkkila, Jean-Yves Winum
Published 2020-01-01

Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation

by Emilie Anduran, Ashok Aspatwar, Nanda-Kumar Parvathaneni, Dennis Suylen, Silvia Bua, Alessio Nocentini, Seppo Parkkila, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Jean-Yves Winum
Published 2020-05-01

Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes

by Ashok Aspatwar, Holger M. Becker, Nanda Kumar Parvathaneni, Milka Hammaren, Aleksandra Svorjova, Harlan Barker, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Mataleena Parikka, Seppo Parkkila, Jean-Yves Winum
Published 2018-01-01

Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish.

by Ashok Aspatwar, Martti E E Tolvanen, Markus J T Ojanen, Harlan R Barker, Anni K Saralahti, Carina A Bäuerlein, Csaba Ortutay, Peiwen Pan, Marianne Kuuslahti, Mataleena Parikka, Mika Rämet, Seppo Parkkila
Published 2015-01-01

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase

by Maarit S. Patrikainen, Martti E.E. Tolvanen, Ashok Aspatwar, Harlan R. Barker, Csaba Ortutay, Janne Jänis, Mikko Laitaoja, Vesa P. Hytönen, Latifeh Azizi, Prajwol Manandhar, Edit Jáger, Daniela Vullo, Sampo Kukkurainen, Mika Hilvo, Claudiu T. Supuran, Seppo Parkkila
Published 2017-12-01