A-431 cell line Australia and New Zealand BH3 protein Cell Death Editorial Fas ligand HT-29 cell line acute myeloid leukemia apoptosis autophagic cell death basic research biochemistry cell death cell survival cellular immunity chronic lymphatic leukemia death receptor drug industry health care organization inhibitor of apoptosis protein liver injury medical research mitochondrial DNA natural killer cell nonhuman professional development pyroptosis telomere transmission electron microscopy treatment outcome