Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit

by Aye, Yimon, Stubbe, JoAnne
Published 2011

Clofarabine Targets the Large Subunit (α) of Human Ribonucleotide Reductase in Live Cells by Assembly into Persistent Hexamers

by Aye, Yimon, Long, Marcus J.C, Chittuluru, Johnathan, Asturias, Francisco J., Stubbe, JoAnne, Brignole, Edward J, Drennan, Catherine L
Published 2013

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound

by Brignole, Edward J, Tsai, Kuang-Lei, Chittuluru, Johnathan, Li, Haoran, Aye, Yimon, Penczek, Pawel A, Stubbe, JoAnne, Drennan, Catherine L., Asturias, Francisco
Published 2018