Ubiquitin Ligases in Cholesterol Metabolism

by Wei Jiang, Bao-Liang Song
Published 2014-06-01

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

by Chang Xie, Xue-Min Gong, Jie Luo, Bo-Liang Li, Bao-Liang Song
Published 2017-03-01

Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption

by Jiang Wang, Bei-Bei Chu, Liang Ge, Bo-Liang Li, Yan Yan, Bao-Liang Song
Published 2009-08-01

Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease.

by Bo-Tao Li, Ming Sun, Yun-Feng Li, Ju-Qiong Wang, Zi-Mu Zhou, Bao-Liang Song, Jie Luo
Published 2020-08-01

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase.

by Shi-You Jiang, Jing-Jie Tang, Xu Xiao, Wei Qi, Suqian Wu, Chao Jiang, Jiaxu Hong, Jianjiang Xu, Bao-Liang Song, Jie Luo
Published 2019-07-01

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis.

by Wei Jiang, Jing-Jie Tang, Hong-Hua Miao, Yu-Xiu Qu, Jie Qin, Jie Xu, Jinbo Yang, Bo-Liang Li, Bao-Liang Song
Published 2014-01-01

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis

by Ao Hu, Xue-Tong Zhao, Heng Tu, Ting Xiao, Ting Fu, Yan Wang, Yong Liu, Xiong-Jie Shi, Jie Luo, Bao-Liang Song
Published 2018-03-01

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

by Jian Xiao, Yanni Xiong, Liu-Ting Yang, Ju-Qiong Wang, Zi-Mu Zhou, Le-Wei Dong, Xiong-Jie Shi, Xiaolu Zhao, Jie Luo, Bao-Liang Song
Published 2020-07-01

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

by Lei Lei, Ying Xiong, Jia Chen, Jin-Bo Yang, Yi Wang, Xin-Ying Yang, Catherine C.Y. Chang, Bao-Liang Song, Ta-Yuan Chang, Bo-Liang Li
Published 2009-06-01

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

by Zhang-Sen Zhou, Mei-Xin Li, Jie Liu, Hengwu Jiao, Jing-Ming Xia, Xiong-Jie Shi, Huabin Zhao, Liping Chu, Jingrong Liu, Wei Qi, Jie Luo, Bao-Liang Song
Published 2020-01-01

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

by Jian Wei, Ying-Yu Zhang, Jie Luo, Ju-Qiong Wang, Yu-Xia Zhou, Hong-Hua Miao, Xiong-Jie Shi, Yu-Xiu Qu, Jie Xu, Bo-Liang Li, Bao-Liang Song
Published 2017-06-01

Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing[S]

by Liang Chen, Mei-Yan Ma, Ming Sun, Lu-Yi Jiang, Xue-Tong Zhao, Xian-Xiu Fang, Sin Man Lam, Guang-Hou Shui, Jie Luo, Xiong-Jie Shi, Bao-Liang Song
Published 2019-10-01

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

by Shi-You Jiang, Hui Li, Jing-Jie Tang, Jie Wang, Jie Luo, Bing Liu, Jin-Kai Wang, Xiong-Jie Shi, Hai-Wei Cui, Jie Tang, Fan Yang, Wei Qi, Wen-Wei Qiu, Bao-Liang Song
Published 2018-12-01

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

by Yamei Han, Zhimin Hu, Aoyuan Cui, Zhengshuai Liu, Fengguang Ma, Yaqian Xue, Yuxiao Liu, Feifei Zhang, Zehua Zhao, Yanyan Yu, Jing Gao, Chun Wei, Jingya Li, Jing Fang, Jia Li, Jian-Gao Fan, Bao-Liang Song, Yu Li
Published 2019-02-01

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine

by Chang Xie 谢畅, Zhang-Sen Zhou 周章森, Na Li 李钠, Yan Bian 卞艳, Yong-Jian Wang 王永建, Li-Juan Wang 王丽娟, Bo-Liang Li 李伯良, Bao-Liang Song 宋保亮
Published 2012-10-01

Identification, clinical manifestation and structural mechanisms of mutations in AMPK associated cardiac glycogen storage disease

by Dan Hu, Dong Hu, Liwen Liu, Daniel Barr, Yang Liu, Norma Balderrabano-Saucedo, Bo Wang, Feng Zhu, Yumei Xue, Shulin Wu, BaoLiang Song, Heather McManus, Katherine Murphy, Katherine Loes, Arnon Adler, Lorenzo Monserrat, Charles Antzelevitch, Michael H. Gollob, Perry M. Elliott, Hector Barajas-Martinez
Published 2020-04-01