Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20S peptidase

by Barthelme, Dominik, Sauer, Robert T
Published 2013

Identification of the Cdc48•20S Proteasome as an Ancient AAA+ Proteolytic Machine

by Barthelme, Dominik, Sauer, Robert T
Published 2014

Origin and Functional Evolution of the Cdc48/p97/VCP AAA+ Protein Unfolding and Remodeling Machine

by Barthelme, Dominik, Sauer, Robert T.
Published 2018

Substrate-guided optimization of the syringolins yields potent proteasome inhibitors with activity against leukemia cell lines

by Totaro, Kyle A., Barthelme, Dominik, Simpson, Peter T., Sello, Jason K., Sauer, Robert T.
Published 2017

Architecture and assembly of the archaeal Cdc48*20S proteasome

by Barthelme, Dominik, Chen, James Z., Grabenstatter, Jonathan Dean, Baker, Tania, Sauer, Robert T
Published 2014

Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium Tuberculosis Proteasome

by Totaro, Kyle A., Barthelme, Dominik, Simpson, Peter T., Jiang, Xiuju, Lin, Gang, Nathan, Carl F., Sauer, Robert T., Sello, Jason K.
Published 2018