Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients.

by Adriana Egui, M Carmen Thomas, Bartolomé Carrilero, Manuel Segovia, Carlos Alonso, Concepción Marañón, Manuel Carlos López
Published 2015-01-01

A proportion of CD4+ T cells from patients with chronic Chagas disease undergo a dysfunctional process, which is partially reversed by benznidazole treatment.

by Elena Pérez-Antón, Adriana Egui, M Carmen Thomas, Bartolomé Carrilero, Marina Simón, Miguel Ángel López-Ruz, Manuel Segovia, Manuel Carlos López
Published 2021-02-01

Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi.

by Adriana Egui, Paola Lasso, María Carmen Thomas, Bartolomé Carrilero, John Mario González, Adriana Cuéllar, Manuel Segovia, Concepción Judith Puerta, Manuel Carlos López
Published 2017-06-01

Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects

by Inmaculada Gómez, M. Carmen Thomas, Génesis Palacios, Adriana Egui, Bartolomé Carrilero, Marina Simón, Basilio Valladares, Basilio Valladares, Manuel Segovia, Emma Carmelo, Emma Carmelo, Manuel Carlos López
Published 2021-09-01