604 Intravenous CMP-001, a CpG-A Toll-like receptor 9 (TLR9) agonist delivered via a virus-like particle, causes tumor regression in syngeneic Hepa1–6 mouse models of hepatocellula...

by Aaron Morris, Arthur Krieg, Evan Walters, Bassel Akache, Michael McCluskie
Published 2020-11-01

Anti-IgE Qb-VLP Conjugate Vaccine Self-Adjuvants through Activation of TLR7

by Bassel Akache, Risini D. Weeratna, Aparna Deora, Jennifer M. Thorn, Brian Champion, James R. Merson, Heather L. Davis, Michael J. McCluskie
Published 2016-01-01

Sulfated archaeol glycolipids: Comparison with other immunological adjuvants in mice.

by Bassel Akache, Felicity C Stark, Yimei Jia, Lise Deschatelets, Renu Dudani, Blair A Harrison, Gerard Agbayani, Dean Williams, Mohammad P Jamshidi, Lakshmi Krishnan, Michael J McCluskie
Published 2018-01-01

Sulfated Lactosyl Archaeol Archaeosomes Synergize with Poly(I:C) to Enhance the Immunogenicity and Efficacy of a Synthetic Long Peptide-Based Vaccine in a Melanoma Tumor Model

by Bassel Akache, Gerard Agbayani, Felicity C. Stark, Yimei Jia, Renu Dudani, Blair A. Harrison, Lise Deschatelets, Vandana Chandan, Edmond Lam, Usha D. Hemraz, Sophie Régnier, Lakshmi Krishnan, Michael J. McCluskie
Published 2021-02-01

The Synergistic Effects of Sulfated Lactosyl Archaeol Archaeosomes When Combined with Different Adjuvants in a Murine Model

by Yimei Jia, Bassel Akache, Gerard Agbayani, Vandana Chandan, Renu Dudani, Blair A. Harrison, Lise Deschatelets, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Felicity C. Stark, Lakshmi Krishnan, Michael J. McCluskie
Published 2021-02-01