Genome-Scale Technology Driven Advances to Research into Normal and Malignant Haematopoiesis

by Berthold Göttgens
Published 2012-01-01

Single-Cell Sequencing in Normal and Malignant Hematopoiesis

by Nicola K. Wilson, Berthold Göttgens
Published 2018-04-01

Determining Physical Mechanisms of Gene Expression Regulation from Single Cell Gene Expression Data.

by Daphne Ezer, Victoria Moignard, Berthold Göttgens, Boris Adryan
Published 2016-08-01

The LMO2 -25 Region Harbours GATA2-Dependent Myeloid Enhancer and RUNX-Dependent T-Lymphoid Repressor Activity.

by Nicolas Bonadies, Berthold Göttgens, Fernando J Calero-Nieto
Published 2015-01-01

Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate.

by Jatin Narula, Aileen M Smith, Berthold Gottgens, Oleg A Igoshin
Published 2010-05-01

Single-cell transcriptome analysis of CAR T-cell products reveals subpopulations, stimulation, and exhaustion signatures

by Xiaonan Wang, Carlotta Peticone, Ekaterini Kotsopoulou, Berthold Göttgens, Fernando J Calero-Nieto
Published 2021-01-01

Coordinated changes in gene expression kinetics underlie both mouse and human erythroid maturation

by Melania Barile, Ivan Imaz-Rosshandler, Isabella Inzani, Shila Ghazanfar, Jennifer Nichols, John C. Marioni, Carolina Guibentif, Berthold Göttgens
Published 2021-07-01

Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

by Rabab Nasrallah, Kathy Knezevic, Thuan Thai, Shane R. Thomas, Berthold Göttgens, Georges Lacaud, Valerie Kouskoff, John E. Pimanda
Published 2015-07-01

PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

by F. Alexander Wolf, Fiona K. Hamey, Mireya Plass, Jordi Solana, Joakim S. Dahlin, Berthold Göttgens, Nikolaus Rajewsky, Lukas Simon, Fabian J. Theis
Published 2019-03-01

Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine

by Leslie L. Glass, Fernando J. Calero-Nieto, Wajid Jawaid, Pierre Larraufie, Richard G. Kay, Berthold Göttgens, Frank Reimann, Fiona M. Gribble
Published 2017-10-01

Clonal Dynamics Reveal Two Distinct Populations of Basal Cells in Slow-Turnover Airway Epithelium

by Julie K. Watson, Steffen Rulands, Adam C. Wilkinson, Aline Wuidart, Marielle Ousset, Alexandra Van Keymeulen, Berthold Göttgens, Cédric Blanpain, Benjamin D. Simons, Emma L. Rawlins
Published 2015-07-01

Itga2b regulation at the onset of definitive hematopoiesis and commitment to differentiation.

by Stephanie Dumon, David S Walton, Giacomo Volpe, Nicola Wilson, Emilie Dassé, Walter Del Pozzo, Josette-Renee Landry, Bryan Turner, Laura P O'Neill, Berthold Göttgens, Jon Frampton
Published 2012-01-01

Mapping and functional characterisation of a CTCF-dependent insulator element at the 3' border of the murine Scl transcriptional domain.

by George A Follows, Rita Ferreira, Mary E Janes, Dominik Spensberger, Francesco Cambuli, Amy F Chaney, Sarah J Kinston, Josette R Landry, Anthony R Green, Berthold Göttgens
Published 2012-01-01

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor

by Martin Wahlestedt, Vasileios Ladopoulos, Isabel Hidalgo, Manuel Sanchez Castillo, Rebecca Hannah, Petter Säwén, Haixia Wan, Monika Dudenhöffer-Pfeifer, Mattias Magnusson, Gudmundur L. Norddahl, Berthold Göttgens, David Bryder
Published 2017-11-01

Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia.

by Nicolas Bonadies, Samuel D Foster, Wai-In Chan, Brynn T Kvinlaug, Dominik Spensberger, Mark A Dawson, Elaine Spooncer, Anthony D Whetton, Andrew J Bannister, Brian J Huntly, Berthold Göttgens
Published 2011-01-01

Three Distinct Patterns of Histone H3Y41 Phosphorylation Mark Active Genes

by Mark A. Dawson, Samuel D. Foster, Andrew J. Bannister, Samuel C. Robson, Rebecca Hannah, Xiaonan Wang, Blerta Xhemalce, Andrew D. Wood, Anthony R. Green, Berthold Göttgens, Tony Kouzarides
Published 2012-09-01

Nanog regulates Pou3f1 expression at the exit from pluripotency during gastrulation

by Antonio Barral, Isabel Rollan, Hector Sanchez-Iranzo, Wajid Jawaid, Claudio Badia-Careaga, Sergio Menchero, Manuel J. Gomez, Carlos Torroja, Fatima Sanchez-Cabo, Berthold Göttgens, Miguel Manzanares, Julio Sainz de Aja
Published 2019-11-01

Single site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses

by Adam C. Wilkinson, Debbie K. Goode, Yi-Han Cheng, Diane E. Dickel, Sam Foster, Tim Sendall, Marloes R. Tijssen, Maria-Jose Sanchez, Len A. Pennacchio, Aileen M. Kirkpatrick, Berthold Göttgens
Published 2013-10-01

Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors

by Serena Belluschi, Emily F. Calderbank, Valerio Ciaurro, Blanca Pijuan-Sala, Antonella Santoro, Nicole Mende, Evangelia Diamanti, Kendig Yen Chi Sham, Xiaonan Wang, Winnie W. Y. Lau, Wajid Jawaid, Berthold Göttgens, Elisa Laurenti
Published 2018-10-01

Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells

by Mari-Liis Kauts, Bianca De Leo, Carmen Rodríguez-Seoane, Roger Ronn, Fokion Glykofrydis, Antonio Maglitto, Polynikis Kaimakis, Margarita Basi, Helen Taylor, Lesley Forrester, Adam C. Wilkinson, Berthold Göttgens, Philippa Saunders, Elaine Dzierzak
Published 2018-10-01