Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes

by Anne Ljungars, Anne Ljungars, Carolin Svensson, Anders Carlsson, Elin Birgersson, Ulla-Carin Tornberg, Björn Frendéus, Mats Ohlin, Mikael Mattsson
Published 2019-07-01

A single-arm, open-label, phase 2 clinical trial evaluating disease response following treatment with BI-505, a human anti-intercellular adhesion molecule-1 monoclonal antibody, in...

by Stina Wichert, Gunnar Juliusson, Åsa Johansson, Elisabeth Sonesson, Ingrid Teige, Anna Teige Wickenberg, Björn Frendeus, Magnus Korsgren, Markus Hansson
Published 2017-01-01

Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing

by Jenny Mattsson, Ludvig Ekdahl, Fredrik Junghus, Ram Ajore, Eva Erlandsson, Abhishek Niroula, Maroulio Pertesi, Björn Frendéus, Ingrid Teige, Björn Nilsson
Published 2021-02-01

594 BT-001, an oncolytic vaccinia virus armed with a Treg-depleting human recombinant anti-CTLA4 antibody and GM-CSF to target the tumor microenvironment

by Laetitia Fend, Eric Quemeneur, Monika Semmrich, Jean-Baptiste Marchand, Matilda Rehn, Nathalie Silvestre, Linda Mårtensson, Johann Foloppe, Ingrid Teige, Björn Frendeus
Published 2020-11-01

FcγRIIb Expression Is Decreased on Naive and Marginal Zone-Like B Cells From Females With Multiple Sclerosis

by Stephanie Trend, Stephanie Trend, Jonatan Leffler, Ingrid Teige, Björn Frendéus, Allan G. Kermode, Allan G. Kermode, Martyn A. French, Prue H. Hart
Published 2021-01-01

725 Pre-clinical development of TNFR2 ligand-blocking BI-1808 for cancer immunotherapy

by Monika Semmrich, Linda Mårtensson, Ingrid Teige, Björn Frendeus, Mathilda Kovacek, Petra Holmkvist, Carolin Svensson, Therese Blidberg, Carl Roos, Andres McAllister, Mimoza Demiri, Marie Borggren, Ingrid Karlsson
Published 2020-11-01

Diet-Induced Abdominal Obesity, Metabolic Changes, and Atherosclerosis in Hypercholesterolemic Minipigs

by Ahmed Ludvigsen Al-Mashhadi, Christian Bo Poulsen, Karin von Wachenfeldt, Anna-Karin Robertson, Jacob Fog Bentzon, Lars Bo Nielsen, Jesper Thygesen, Lars Poulsen Tolbod, Jens Rolighed Larsen, Søren Kragh Moestrup, Björn Frendéus, Brynjulf Mortensen, Ludovic Drouet, Rozh H. Al-Mashhadi, Erling Falk
Published 2018-01-01

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation

by Muchaala Yeboah, Charys Papagregoriou, Des C. Jones, H.T. Claude Chan, Guangan Hu, Justine S. McPartlan, Torbjörn Schiött, Ulrika Mattson, C. Ian Mockridge, Ulla-Carin Tornberg, Björn Hambe, Anne Ljungars, Mikael Mattsson, Ivo Tews, Martin J. Glennie, Stephen M. Thirdborough, John Trowsdale, Björn Frendeus, Jianzhu Chen, Mark S. Cragg, Ali Roghanian
Published 2020-09-01