ATF6 Is a Critical Determinant of CHOP Dynamics during the Unfolded Protein Response

by Huan Yang, Marije Niemeijer, Bob van de Water, Joost B. Beltman
Published 2020-02-01

Identification of cisplatin-regulated metabolic pathways in pluripotent stem cells.

by Louise von Stechow, Ainhoa Ruiz-Aracama, Bob van de Water, Ad Peijnenburg, Erik Danen, Arjen Lommen
Published 2013-01-01

Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening.

by Zi Di, Bram Herpers, Lisa Fredriksson, Kuan Yan, Bob van de Water, Fons J Verbeek, John H N Meerman
Published 2012-01-01

Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer

by Keren Yizhak, Edoardo Gaude, Sylvia Le Dévédec, Yedael Y Waldman, Gideon Y Stein, Bob van de Water, Christian Frezza, Eytan Ruppin
Published 2014-11-01

Mining a human transcriptome database for chemical modulators of NRF2.

by John P Rooney, Brian Chorley, Steven Hiemstra, Steven Wink, Xuting Wang, Douglas A Bell, Bob van de Water, J Christopher Corton
Published 2020-01-01

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

by Elias Zgheib, Alice Limonciel, Xiaoqi Jiang, Anja Wilmes, Steven Wink, Bob van de Water, Annette Kopp-Schneider, Frederic Y. Bois, Paul Jennings
Published 2018-10-01

Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

by Elias Zgheib, Alice Limonciel, Xiaoqi Jiang, Anja Wilmes, Steven Wink, Bob van de Water, Annette Kopp-Schneider, Frederic Y. Bois, Paul Jennings
Published 2019-06-01

Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors

by Huan Yang, Wanda van der Stel, Randy Lee, Caroline Bauch, Sam Bevan, Paul Walker, Bob van de Water, Erik H. J. Danen, Joost B. Beltman
Published 2021-08-01

Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention

by Esmee Koedoot, Eline van Steijn, Marjolein Vermeer, Román González-Prieto, Alfred C. O. Vertegaal, John W. M. Martens, Sylvia E. Le Dévédec, Bob van de Water
Published 2021-03-01

Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.

by Zi Di, Maarten J D Klop, Vasiliki-Maria Rogkoti, Sylvia E Le Dévédec, Bob van de Water, Fons J Verbeek, Leo S Price, John H N Meerman
Published 2014-01-01

Automated whole animal bio-imaging assay for human cancer dissemination.

by Veerander P S Ghotra, Shuning He, Hans de Bont, Wietske van der Ent, Herman P Spaink, Bob van de Water, B Ewa Snaar-Jagalska, Erik H J Danen
Published 2012-01-01

A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy

by Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang, Bob van de Water
Published 2019-07-01

Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.

by Carla S Verissimo, Rachel Elands, Sou Cheng, Dirk-Jan Saaltink, Judith P ter Horst, Maria N Alme, Chantal Pont, Bob van de Water, Bjarte Håvik, Carlos P Fitzsimons, Erno Vreugdenhil
Published 2013-01-01

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy

by Esmee Koedoot, Liesanne Wolters, Marcel Smid, Peter Stoilov, Gerhard A. Burger, Bram Herpers, Kuan Yan, Leo S. Price, John W. M. Martens, Sylvia E. Le Dévédec, Bob van de Water
Published 2021-03-01

Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells

by Yongjie Zhang, Yongjie Zhang, Shalenie P. den Braver-Sewradj, Michiel W. den Braver, Steven Hiemstra, Nico P. E. Vermeulen, Bob van de Water, Jan N. M. Commandeur, J. C. Vos
Published 2018-04-01

Utility of Extrapolating Human S1500+ Genes to the Whole Transcriptome: Tunicamycin Case Study

by Deepak Mav, Dhiral P Phadke, Michele R Balik-Meisner, B Alex Merrick, Scott Auerbach, Marije Niemeijer, Suzanna Huppelschoten, Audrey Baze, Celine Parmentier, Lysiane Richert, Bob van de Water, Ruchir R Shah, Richard S Paules
Published 2020-09-01

Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

by Esmee Koedoot, Michiel Fokkelman, Vasiliki-Maria Rogkoti, Marcel Smid, Iris van de Sandt, Hans de Bont, Chantal Pont, Janna E. Klip, Steven Wink, Mieke A. Timmermans, Erik A. C. Wiemer, Peter Stoilov, John A. Foekens, Sylvia E. Le Dévédec, John W. M. Martens, Bob van de Water
Published 2019-07-01

A screening-based approach identifies cell cycle regulators AURKA, CHK1 and PLK1 as targetable regulators of chondrosarcoma cell survival

by Yvonne de Jong, Fairuz Bennani, Jolieke G. van Oosterwijk, Gaia Alberti, Zuzanna Baranski, Pauline Wijers-Koster, Sanne Venneker, Inge H. Briaire-de Bruijn, Brendy E. van de Akker, Hans Baelde, Anne-Marie Cleton-Jansen, Bob van de Water, Erik H.J. Danen, Judith V.M.G. Bovée
Published 2019-12-01

Current EU research activities on combined exposure to multiple chemicals

by Stephanie K. Bopp, Robert Barouki, Werner Brack, Silvia Dalla Costa, Jean-Lou C.M. Dorne, Paula E. Drakvik, Michael Faust, Tuomo K. Karjalainen, Stylianos Kephalopoulos, Jacob van Klaveren, Marike Kolossa-Gehring, Andreas Kortenkamp, Erik Lebret, Teresa Lettieri, Sofie Nørager, Joëlle Rüegg, Jose V. Tarazona, Xenia Trier, Bob van de Water, Jos van Gils, Åke Bergman
Published 2018-11-01

Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment

by Elina Drakvik, Rolf Altenburger, Yasunobu Aoki, Thomas Backhaus, Tina Bahadori, Robert Barouki, Werner Brack, Mark T.D. Cronin, Barbara Demeneix, Susanne Hougaard Bennekou, Jacob van Klaveren, Carsten Kneuer, Marike Kolossa-Gehring, Erik Lebret, Leo Posthuma, Lena Reiber, Cynthia Rider, Joëlle Rüegg, Giuseppe Testa, Bart van der Burg, Hilko van der Voet, A. Michael Warhurst, Bob van de Water, Kunihiko Yamazaki, Mattias Öberg, Åke Bergman
Published 2020-01-01