A d‑Amino Acid at the N‑Terminus of a Protein Abrogates Its Degradation by the N‑End Rule Pathway

by Amy E. Rabideau, Bradley L. Pentelute
Published 2015-11-01

Salt Effect Accelerates Site-Selective Cysteine Bioconjugation

by Peng Dai, Chi Zhang, Matthew Welborn, James J. Shepherd, Tianyu Zhu, Troy Van Voorhis, Bradley L. Pentelute
Published 2016-08-01

A structural and mechanistic study of π-clamp-mediated cysteine perfluoroarylation

by Peng Dai, Jonathan K. Williams, Chi Zhang, Matthew Welborn, James J. Shepherd, Tianyu Zhu, Troy Van Voorhis, Mei Hong, Bradley L. Pentelute
Published 2017-08-01

Ultra-large chemical libraries for the discovery of high-affinity peptide binders

by Anthony J. Quartararo, Zachary P. Gates, Bente A. Somsen, Nina Hartrampf, Xiyun Ye, Arisa Shimada, Yasuhiro Kajihara, Christian Ottmann, Bradley L. Pentelute
Published 2020-06-01

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

by Choi-Fong Cho, Justin M. Wolfe, Colin M. Fadzen, David Calligaris, Kalvis Hornburg, E. Antonio Chiocca, Nathalie Y. R. Agar, Bradley L. Pentelute, Sean E. Lawler
Published 2017-06-01

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

by Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael Rogers, Bradley L Pentelute, Jonathan M Carlson, Mark Hixon, Diane Joseph-McCarthy, Arijit Chakravarty
Published 2021-01-01

Mucosal absorption of therapeutic peptides by harnessing the endogenous sorting of glycosphingolipids

by Maria Daniela Garcia-Castillo, Daniel J-F Chinnapen, Yvonne M te Welscher, Rodrigo J Gonzalez, Samir Softic, Michele Pacheco, Randall J Mrsny, C Ronald Kahn, Ulrich H von Andrian, Jesper Lau, Bradley L Pentelute, Wayne I Lencer
Published 2018-05-01

Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers

by Chengxi Li, Alex J. Callahan, Mark D. Simon, Kyle A. Totaro, Alexander J. Mijalis, Kruttika-Suhas Phadke, Genwei Zhang, Nina Hartrampf, Carly K. Schissel, Ming Zhou, Hong Zong, Gunnar J. Hanson, Andrei Loas, Nicola L. B. Pohl, David E. Verhoeven, Bradley L. Pentelute
Published 2021-07-01

Automated flow peptide synthesis

by Mijalis, Alexander James
Published 2018

Peptide conjugation to enhance oligonucleotide delivery

by Wolfe, Justin Mahoney
Published 2018

Long peptides for cysteine arylation

by Evans, Ethan Daniel
Published 2018

Investigation and application of heterochiral proteins enabled by flow-based peptide synthesis

by Mong, Surin Khai
Published 2018

Peptide-mediated delivery of antisense oligonucleotides and chemotherapeutics across biological barriers

by Fadzen, Colin MacLaine
Published 2018

Fast flow biopolymer synthesis

by Simon, Mark David
Published 2018

Site-selective modification of cysteine residues

by Dai, Peng, Ph. D. Massachusetts Institute of Technology
Published 2018

Cysteine arylation

by Zhang, Chi, Ph. D. Massachusetts Institute of Technology, Department of Chemistry
Published 2017

New methods for synthesis and modification of peptides and proteins

by Vinogradov, Alexander Alexandrovich
Published 2017

Protective antigen-mediated delivery of biomolecules

by Lu, Zeyu (Zeyu Mike)
Published 2019

Palladium reagents for bioconjugation

by Rojas, Anthony J. (Anthony Jose)
Published 2019