Expression of the Rap1 guanine nucleotide exchange factor, MR-GEF, is altered in individuals with bipolar disorder.

by Angela Bithell, Tony Hsu, Apsara Kandanearatchi, Sabine Landau, Ian P Everall, Ming T Tsuang, Gursharan Chana, Brenda P Williams
Published 2010-04-01

Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis

by Jenny Lange, Luke J. Haslett, Emyr Lloyd-Evans, Jennifer M. Pocock, Mark S. Sands, Brenda P. Williams, Jonathan D. Cooper
Published 2018-08-01

Rest-mediated regulation of extracellular matrix is crucial for neural development.

by Yuh-Man Sun, Megan Cooper, Sophie Finch, Hsuan-Hwai Lin, Zhou-Feng Chen, Brenda P Williams, Noel J Buckley
Published 2008-01-01

Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Cln3−/− Mice

by Marta A. Tarczyluk-Wells, Christoph Salzlechner, Allison R. Najafi, Ming J. Lim, Ming J. Lim, David Smith, Frances M. Platt, Brenda P. Williams, Jonathan D. Cooper, Jonathan D. Cooper, Jonathan D. Cooper
Published 2019-09-01

Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons

by Lotta Parviainen, Sybille Dihanich, Greg W. Anderson, Andrew M. Wong, Helen R. Brooks, Rosella Abeti, Payam Rezaie, Giovanna Lalli, Simon Pope, Simon J. Heales, Hannah M. Mitchison, Brenda P. Williams, Jonathan D. Cooper
Published 2017-10-01