Brian David Dynlacht
Brian David Dynlacht (born September 3, 1965 in
Brooklyn, New York), is an American biochemist and professor in the department of pathology of
New York University Grossman School of Medicine at
NYU Langone Health. Before moving his lab to
New York University, he was an associate professor in the department of molecular and cellular biology at
Harvard University. In 2002, while researching at the
Harvard University, Dynlacht reported the discovery of CP110, which is now thought to be at the center of a
molecular switch governing the
centriole to
ciliary transition in mammalian cells. His lab identified the first centriolar deubiquitinating enzyme, USP33, whose expression regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110, and thus regulates the centrosome duplication.
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