Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

by Brian C. Monk, Mikhail V. Keniya
Published 2021-01-01

Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens

by Katharina Rosam, Brian C. Monk, Michaela Lackner
Published 2021-12-01

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of <i>Candida albicans</i>

by Atanu Banerjee, Jorgaq Pata, Suman Sharma, Brian C. Monk, Pierre Falson, Rajendra Prasad
Published 2021-01-01

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance.

by Mikhail V Keniya, Edmond Fleischer, Anette Klinger, Richard D Cannon, Brian C Monk
Published 2015-01-01

Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals.

by Joel D A Tyndall, Manya Sabherwal, Alia A Sagatova, Mikhail V Keniya, Jacopo Negroni, Rajni K Wilson, Matthew A Woods, Klaus Tietjen, Brian C Monk
Published 2016-01-01

[Fe2L3]4+ Cylinders Derived from Bis(bidentate) 2-Pyridyl-1,2,3-triazole “Click” Ligands: Synthesis, Structures and Exploration of Biological Activity

by James D. Crowley, Christopher M. Fitchett, Lyall R. Hanton, Brian C. Monk, Alia Sagatova, Joel D. A. Tyndall, Madhu Shankar, James E. M. Lewis, Sreedhar K. Vellas
Published 2013-05-01