Loss of the integrin-activating transmembrane protein Fam38A (Piezo1) promotes a switch to a reduced integrin-dependent mode of cell migration.

by Brian J McHugh, Amanda Murdoch, Christopher Haslett, Tariq Sethi
Published 2012-01-01

Human cathelicidin production by the cervix.

by Lorraine Frew, Sofia Makieva, Andrew T M McKinlay, Brian J McHugh, Ann Doust, Jane E Norman, Donald J Davidson, Sarah J Stock
Published 2014-01-01

The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus.

by Silke M Currie, Emily Gwyer Findlay, Brian J McHugh, Annie Mackellar, Tian Man, Derek Macmillan, Hongwei Wang, Paul M Fitch, Jürgen Schwarze, Donald J Davidson
Published 2013-01-01

Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa.

by Brian J McHugh, Rongling Wang, Hsin-Ni Li, Paula E Beaumont, Rebekah Kells, Holly Stevens, Lisa Young, Adriano G Rossi, Robert D Gray, Julia R Dorin, Emily L Gwyer Findlay, David Brough, Donald J Davidson
Published 2019-04-01

Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy

by Emily Gwyer Findlay, Andrew J. Currie, Ailiang Zhang, Jana Ovciarikova, Lisa Young, Holly Stevens, Brian J. McHugh, Marta Canel, Mohini Gray, Simon W.F. Milling, John D.M. Campbell, John Savill, Alan Serrels, Donald J. Davidson
Published 2019-08-01