Nfkb1 inhibits LPS-induced IFN-β and IL-12 p40 production in macrophages by distinct mechanisms.

by Xixing Zhao, Erik J Ross, Yanyan Wang, Bruce H Horwitz
Published 2012-01-01

Pathogenic intestinal bacteria enhance prostate cancer development via systemic activation of immune cells in mice.

by Theofilos Poutahidis, Kelsey Cappelle, Tatiana Levkovich, Chung-Wei Lee, Michael Doulberis, Zhongming Ge, James G Fox, Bruce H Horwitz, Susan E Erdman
Published 2013-01-01

Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

by Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz
Published 2017-07-01

WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis

by Amlan Biswas, Dror S. Shouval, Alexandra Griffith, Jeremy A. Goettel, Michael Field, Yu Hui Kang, Liza Konnikova, Erin Janssen, Naresh Singh Redhu, Adrian J. Thrasher, Talal Chatila, Vijay K. Kuchroo, Raif S Geha, Luigi D. Notarangelo, Sung-Yun Pai, Bruce H. Horwitz, Scott B. Snapper
Published 2018-05-01

Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis

by Grigory Ryzhakov, Nathaniel R. West, Fanny Franchini, Simon Clare, Nicholas E. Ilott, Stephen N. Sansom, Samuel J. Bullers, Claire Pearson, Alice Costain, Alun Vaughan-Jackson, Jeremy A. Goettel, Joerg Ermann, Bruce H. Horwitz, Ludovico Buti, Xin Lu, Subhankar Mukhopadhyay, Scott B. Snapper, Fiona Powrie
Published 2018-09-01