Resistance Mutations to BTK Inhibitors Originate From the NF-κB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway

by C. I. Edvard Smith, Jan A. Burger
Published 2021-06-01

Oligonucleotide–Palladacycle Conjugates as Splice-Correcting Agents

by Madhuri Hande, Osama Saher, Karin E. Lundin, C. I. Edvard Smith, Rula Zain, Tuomas Lönnberg
Published 2019-03-01

B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing.

by Dara K Mohammad, Raja H Ali, Janne J Turunen, Beston F Nore, C I Edvard Smith
Published 2016-01-01

Differential evolutionary wiring of the tyrosine kinase Btk.

by Hossain M Nawaz, Per Kylsten, Noriko Hamada, Daisuke Yamamoto, C I Edvard Smith, Jessica M Lindvall
Published 2012-01-01

Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects

by H. Yesid Estupiñán, H. Yesid Estupiñán, Anna Berglöf, Rula Zain, Rula Zain, C. I. Edvard Smith
Published 2021-03-01

Diagnostics of primary immunodeficiency diseases: a sequencing capture approach.

by Lotte N Moens, Elin Falk-Sörqvist, A Charlotta Asplund, Ewa Bernatowska, C I Edvard Smith, Mats Nilsson
Published 2014-01-01

Oligonucleotide Binding to Non-B-DNA in MYC

by Tea Umek, Karin Sollander, Helen Bergquist, Jesper Wengel, Karin E. Lundin, C.I. Edvard Smith, Rula Zain
Published 2019-03-01

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration

by Thomas C. Roberts, K. Emelie M. Blomberg, C.I. Edvard Smith, Samir EL Andaloussi, Matthew J.A. Wood
Published 2016-03-01

Differential B-Cell Receptor Signaling Requirement for Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells

by Laia Sadeghi, Gustav Arvidsson, Magali Merrien, Agata M.Wasik, André Görgens, C.I. Edvard Smith, Birgitta Sander, Anthony P. Wright
Published 2020-05-01

The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study.

by You Xu, Olof Gissberg, Y Vladimir Pabon-Martinez, Jesper Wengel, Karin E Lundin, C I Edvard Smith, Rula Zain, Lennart Nilsson, Alessandra Villa
Published 2019-01-01

ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library.

by Manuela O Gustafsson, Dara K Mohammad, Erkko Ylösmäki, Hyunseok Choi, Subhash Shrestha, Qing Wang, Beston F Nore, Kalle Saksela, C I Edvard Smith
Published 2017-01-01

Role of Pseudoisocytidine Tautomerization in Triplex-Forming Oligonucleotides: In Silico and in Vitro Studies

by Yossa Dwi Hartono, Y. Vladimir Pabon-Martinez, Arzu Uyar, Jesper Wengel, Karin E. Lundin, Rula Zain, C. I. Edvard Smith, Lennart Nilsson, Alessandra Villa
Published 2017-05-01

Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report

by Karin E. Lundin, Qing Wang, Abdulrahman Hamasy, Per Marits, Mehmet Uzunel, Valtteri Wirta, Ann-Charlotte Wikström, Anders Fasth, Olov Ekwall, C.I. Edvard Smith
Published 2018-08-01

Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting.

by Helen Bergquist, Cristina S J Rocha, Rubén Álvarez-Asencio, Chi-Hung Nguyen, Mark W Rutland, C I Edvard Smith, Liam Good, Peter E Nielsen, Rula Zain
Published 2016-01-01

Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia

by Tom A. Mulder, Lucía Peña-Pérez, Anna Berglöf, Stephan Meinke, H. Yesid Estupiñán, Kia Heimersson, Rula Zain, Robert Månsson, C. I. Edvard Smith, Marzia Palma
Published 2021-05-01

Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides

by Haneen Daralnakhla, Osama Saher, Susanna Zamolo, Safa Bazaz, Jeremy P. Bost, Marc Heitz, Karin E. Lundin, Samir EL Andaloussi, Tamis Darbre, Jean-Louis Reymond, Rula Zain, C. I. Edvard Smith
Published 2021-01-01

Ischemia-reperfusion injury and pregnancy initiate time-dependent and robust signs of up-regulation of cardiac progenitor cells.

by Rami Genead, Helene Fischer, Alamdar Hussain, Marie Jaksch, Agneta B Andersson, Karin Ljung, Ivana Bulatovic, Anders Franco-Cereceda, Elzafir Elsheikh, Matthias Corbascio, C I Edvard Smith, Christer Sylvén, Karl-Henrik Grinnemo
Published 2012-01-01

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo

by Safa Bazaz, Tõnis Lehto, Rahel Tops, Olof Gissberg, Dhanu Gupta, Burcu Bestas, Jeremy Bost, Oscar P. B. Wiklander, Helena Sork, Eman M. Zaghloul, Doste R. Mamand, Mattias Hällbrink, Rannar Sillard, Osama Saher, Kariem Ezzat, C. I. Edvard Smith, Samir EL Andaloussi, Taavi Lehto
Published 2021-08-01

Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells

by Agneta Månsson-Broberg, Sergey Rodin, Ivana Bulatovic, Cristián Ibarra, Marie Löfling, Rami Genead, Eva Wärdell, Ulrika Felldin, Carl Granath, Evren Alici, Katarina Le Blanc, C.I. Edvard Smith, Alena Salašová, Magnus Westgren, Erik Sundström, Per Uhlén, Ernest Arenas, Christer Sylvén, Karl Tryggvason, Matthias Corbascio, Oscar E. Simonson, Cecilia Österholm, Karl-Henrik Grinnemo
Published 2016-04-01