A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014).

by Ifeanyi Valentine Uche, Calman A MacLennan, Allan Saul
Published 2017-01-01

Early interferon-γ production in human lymphocyte subsets in response to nontyphoidal Salmonella demonstrates inherent capacity in innate cells.

by Tonney S Nyirenda, Anna E Seeley, Wilson L Mandala, Mark T Drayson, Calman A MacLennan
Published 2010-10-01

Strain Selection for Generation of O-Antigen-Based Glycoconjugate Vaccines against Invasive Nontyphoidal Salmonella Disease.

by Luisa Lanzilao, Giuseppe Stefanetti, Allan Saul, Calman A MacLennan, Francesca Micoli, Simona Rondini
Published 2015-01-01

Cross-sectional study of IgG antibody levels to invasive nontyphoidal Salmonella LPS O-antigen with age in Uganda [version 1; peer review: 2 approved]

by Lisa Stockdale, Angela Nalwoga, Stephen Nash, Sean Elias, Gershim Asiki, Sylvia Kusemererwa, James J. Gilchrist, Robert Newton, Calman A. MacLennan
Published 2019-06-01

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi.

by Chisomo L Msefula, Robert A Kingsley, Melita A Gordon, Elizabeth Molyneux, Malcolm E Molyneux, Calman A MacLennan, Gordon Dougan, Robert S Heyderman
Published 2012-01-01

Relationship between antibody susceptibility and lipopolysaccharide O-antigen characteristics of invasive and gastrointestinal nontyphoidal Salmonellae isolates from Kenya.

by Robert S Onsare, Francesca Micoli, Luisa Lanzilao, Renzo Alfini, Chinyere K Okoro, Anne W Muigai, Gunturu Revathi, Allan Saul, Samuel Kariuki, Calman A MacLennan, Simona Rondini
Published 2015-03-01

An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei.

by Mariaelena Caboni, Thierry Pédron, Omar Rossi, David Goulding, Derek Pickard, Francesco Citiulo, Calman A MacLennan, Gordon Dougan, Nicholas R Thomson, Allan Saul, Philippe J Sansonetti, Christiane Gerke
Published 2015-03-01

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1.

by Arianna Marini, Omar Rossi, Maria Grazia Aruta, Francesca Micoli, Simona Rondini, Serafina Guadagnuolo, Isabel Delany, Ian R Henderson, Adam F Cunningham, Allan Saul, Calman A MacLennan, Oliver Koeberling
Published 2017-01-01

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313 [v...

by Edna M. Ondari, Elizabeth J. Klemm, Chisomo L. Msefula, Moataz Abd El Ghany, Jennifer N. Heath, Derek J. Pickard, Lars Barquist, Gordon Dougan, Robert A. Kingsley, Calman A. MacLennan
Published 2019-04-01

Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen.

by Peter J Hart, Colette M O'Shaughnessy, Matthew K Siggins, Saeeda Bobat, Robert A Kingsley, David A Goulding, John A Crump, Hugh Reyburn, Francesca Micoli, Gordon Dougan, Adam F Cunningham, Calman A MacLennan
Published 2016-01-01

Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection.

by Yun Shan Goh, Francesca Necchi, Colette M O'Shaughnessy, Francesca Micoli, Massimiliano Gavini, Stephen P Young, Chisomo L Msefula, Esther N Gondwe, Wilson L Mandala, Melita A Gordon, Allan J Saul, Calman A MacLennan
Published 2016-04-01

Presentation of life-threatening invasive nontyphoidal Salmonella disease in Malawian children: A prospective observational study.

by Calman A MacLennan, Chisomo L Msefula, Esther N Gondwe, James J Gilchrist, Paul Pensulo, Wilson L Mandala, Grace Mwimaniwa, Meraby Banda, Julia Kenny, Lorna K Wilson, Amos Phiri, Jenny M MacLennan, Elizabeth M Molyneux, Malcolm E Molyneux, Stephen M Graham
Published 2017-12-01

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium.

by Vanessa K Wong, Derek J Pickard, Lars Barquist, Karthikeyan Sivaraman, Andrew J Page, Peter J Hart, Mark J Arends, Kathryn E Holt, Leanne Kane, Lynda F Mottram, Louise Ellison, Ruben Bautista, Chris J McGee, Sally J Kay, Thomas M Wileman, Linda J Kenney, Calman A MacLennan, Robert A Kingsley, Gordon Dougan
Published 2013-01-01

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

by James J. Gilchrist, Anna Rautanen, Benjamin P. Fairfax, Tara C. Mills, Vivek Naranbhai, Holly Trochet, Matti Pirinen, Esther Muthumbi, Salim Mwarumba, Patricia Njuguna, Neema Mturi, Chisomo L. Msefula, Esther N. Gondwe, Jenny M. MacLennan, Stephen J. Chapman, Malcolm E. Molyneux, Julian C. Knight, Chris C. A. Spencer, Thomas N. Williams, Calman A. MacLennan, J. Anthony G. Scott, Adrian V. S. Hill
Published 2018-03-01

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates

by Anna E. Schager, C. Coral Dominguez-Medina, Francesca Necchi, Francesca Micoli, Yun Shan Goh, Margaret Goodall, Adriana Flores-Langarica, Saeeda Bobat, Charlotte N. L. Cook, Melissa Arcuri, Arianna Marini, Lloyd D. W. King, Faye C. Morris, Graham Anderson, Kai-Michael Toellner, Ian R. Henderson, Constantino López-Macóías, Calman A. MacLennan, Adam F. Cunningham, Martin Fabian Bachmann, Stefan H. E. Kaufmann
Published 2018-03-01

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

by C. Coral Domínguez-Medina, Marisol Pérez-Toledo, Anna E. Schager, Jennifer L. Marshall, Charlotte N. Cook, Saeeda Bobat, Hyea Hwang, Byeong Jae Chun, Erin Logan, Jack A. Bryant, Will M. Channell, Faye C. Morris, Sian E. Jossi, Areej Alshayea, Amanda E. Rossiter, Paul A. Barrow, William G. Horsnell, Calman A. MacLennan, Ian R. Henderson, Jeremy H. Lakey, James C. Gumbart, Constantino López-Macías, Vassiliy N. Bavro, Adam F. Cunningham
Published 2020-02-01

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa.

by International Typhoid Consortium, Vanessa K Wong, Kathryn E Holt, Chinyere Okoro, Stephen Baker, Derek J Pickard, Florian Marks, Andrew J Page, Grace Olanipekun, Huda Munir, Roxanne Alter, Paul D Fey, Nicholas A Feasey, Francois-Xavier Weill, Simon Le Hello, Peter J Hart, Samuel Kariuki, Robert F Breiman, Melita A Gordon, Robert S Heyderman, Jan Jacobs, Octavie Lunguya, Chisomo Msefula, Calman A MacLennan, Karen H Keddy, Anthony M Smith, Robert S Onsare, Elizabeth De Pinna, Satheesh Nair, Ben Amos, Gordon Dougan, Stephen Obaro
Published 2016-09-01