The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer.

by Mark Bates, Cathy D Spillane, Michael F Gallagher, Amanda McCann, Cara Martin, Gordon Blackshields, Helen Keegan, Luke Gubbins, Robert Brooks, Doug Brooks, Stavros Selemidis, Sharon O'Toole, John J O'Leary
Published 2020-01-01

Towards a “Sample-In, Answer-Out” Point-of-Care Platform for Nucleic Acid Extraction and Amplification: Using an HPV E6/E7 mRNA Model System

by Anja Gulliksen, Helen Keegan, Cara Martin, John O'Leary, Lars A. Solli, Inger Marie Falang, Petter Grønn, Aina Karlgård, Michal M. Mielnik, Ib-Rune Johansen, Terje R. Tofteberg, Tobias Baier, Rainer Gransee, Klaus Drese, Thomas Hansen-Hagge, Lutz Riegger, Peter Koltay, Roland Zengerle, Frank Karlsen, Dag Ausen, Liv Furuberg
Published 2012-01-01

Platelet adhesion and degranulation induce pro-survival and pro-angiogenic signalling in ovarian cancer cells.

by Karl Egan, Darragh Crowley, Paul Smyth, Sharon O'Toole, Cathy Spillane, Cara Martin, Michael Gallagher, Aoife Canney, Lucy Norris, Niamh Conlon, Lynda McEvoy, Brendan Ffrench, Britta Stordal, Helen Keegan, Stephen Finn, Victoria McEneaney, Alex Laios, Jens Ducrée, Eimear Dunne, Leila Smith, Michael Berndt, Orla Sheils, Dermot Kenny, John O'Leary
Published 2011-01-01

Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening

by John J. O'Leary, Sharon A. O'Toole, Feras Abu Saadeh, Charles d'Adhemar, Lucy Norris, Ream Langhe, Tom D'Arcy, Noreen Gleeson, Margaret Lawson, Orla Sheils, Martina Ring, Anthony Davies, Cara Martin, Lynda McEvoy, Stephen Finn, Michael Gallagher, Lynne Kelly, Alexandros Laios, Richard Flavin, Bashir M. Mohamed
Published 2013-01-01

The induction of a mesenchymal phenotype by platelet cloaking of cancer cells is a universal phenomenon

by Cathy D. Spillane, Niamh M. Cooke, Mark P. Ward, Dermot Kenny, Gordon Blackshields, Tanya Kelly, Mark Bates, Yanmei Huang, Cara Martin, Sinead Skehan, Aoife Canney, Michael Gallagher, Paul Smyth, Nathan Brady, Andres Clarke, Bashir Mohamed, Lucy Norris, Doug A. Brooks, Robert D. Brooks, Jessica K. Heatlie, Stavros Selemidis, Sean Hanniffy, Eric Dixon, Orla Sheils, Sharon A. O'Toole, John J. O'Leary
Published 2021-12-01