Disease Modifiers of Inherited SCN5A Channelopathy

by Arie O. Verkerk, Arie O. Verkerk, Ahmad S. Amin, Carol Ann Remme
Published 2018-10-01

KV4.3 Expression Modulates NaV1.5 Sodium Current

by Vincent Portero, Ronald Wilders, Simona Casini, Flavien Charpentier, Arie O. Verkerk, Arie O. Verkerk, Carol Ann Remme
Published 2018-03-01

A heterozygous deletion mutation in the cardiac sodium channel gene SCN5A with loss- and gain-of-function characteristics manifests as isolated conduction disease, without signs of...

by Sven Zumhagen, Marieke W Veldkamp, Birgit Stallmeyer, Antonius Baartscheer, Lars Eckardt, Matthias Paul, Carol Ann Remme, Zahurul A Bhuiyan, Connie R Bezzina, Eric Schulze-Bahr
Published 2013-01-01

Low human dystrophin levels prevent cardiac electrophysiological and structural remodelling in a Duchenne mouse model

by Gerard A. Marchal, Maaike van Putten, Arie O. Verkerk, Simona Casini, Kayleigh Putker, Shirley C. M. van Amersfoorth, Annemieke Aartsma-Rus, Elisabeth M. Lodder, Carol Ann Remme
Published 2021-05-01

Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp

by Arie O. Verkerk, Arie O. Verkerk, Gerard A. Marchal, Jan G. Zegers, Makiri Kawasaki, Antoine H. G. Driessen, Carol Ann Remme, Joris R. de Groot, Ronald Wilders
Published 2021-04-01

Functional Consequences of the <i>SCN5A</i>-p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice

by Simona Casini, Maxime Albesa, Zizun Wang, Vincent Portero, Daniela Ross-Kaschitza, Jean-Sébastien Rougier, Gerard A. Marchal, Wendy K. Chung, Connie R. Bezzina, Hugues Abriel, Carol Ann Remme
Published 2019-10-01

Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction.

by Elisabeth M Lodder, Brendon P Scicluna, Annalisa Milano, Albert Y Sun, Hao Tang, Carol Ann Remme, Perry D Moerland, Michael W T Tanck, Geoffrey S Pitt, Douglas A Marchuk, Connie R Bezzina
Published 2012-01-01

Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel

by Marieke W. Veldkamp, Guillaume S. C. Geuzebroek, Antonius Baartscheer, Arie O. Verkerk, Cees A. Schumacher, Gedeon G. Suarez, Wouter R. Berger, Simona Casini, Shirley C. M. van Amersfoorth, Koen T. Scholman, Antoine H. G. Driessen, Charly N. W. Belterman, Antoni C. G. van Ginneken, Joris R. de Groot, Jacques M. T. de Bakker, Carol Ann Remme, Bas J. Boukens, Ruben Coronel
Published 2018-10-01