Inference of Candidate Germline Mutator Loci in Humans from Genome-Wide Haplotype Data.

by Cathal Seoighe, Aylwyn Scally
Published 2017-01-01

Integrative analysis of mRNA expression and half-life data reveals trans-acting genetic variants associated with increased expression of stable transcripts.

by Thong T Nguyen, Cathal Seoighe
Published 2013-01-01

Impact of the Choice of Normalization Method on Molecular Cancer Class Discovery Using Nonnegative Matrix Factorization.

by Haixuan Yang, Cathal Seoighe
Published 2016-01-01

Heritability in the efficiency of nonsense-mediated mRNA decay in humans.

by Cathal Seoighe, Chris Gehring
Published 2010-01-01

vcfView: An Extensible Data Visualization and Quality Assurance Platform for Integrated Somatic Variant Analysis

by Brian O’Sullivan, Cathal Seoighe
Published 2020-11-01

Frequent toggling between alternative amino acids is driven by selection in HIV-1.

by Wayne Delport, Konrad Scheffler, Cathal Seoighe
Published 2008-12-01

Gametophytic selection in Arabidopsis thaliana supports the selective model of intron length reduction.

by Cathal Seoighe, Chris Gehring, Laurence D Hurst
Published 2005-08-01

Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data.

by Yu Kong, Deepa Rastogi, Cathal Seoighe, John M Greally, Masako Suzuki
Published 2019-01-01

Controlling for background genetic effects using polygenic scores improves the power of genome-wide association studies

by Declan Bennett, Donal O’Shea, John Ferguson, Derek Morris, Cathal Seoighe
Published 2021-10-01

The hidden geometries of the Arabidopsis thaliana epidermis.

by Lee Staff, Patricia Hurd, Lara Reale, Cathal Seoighe, Alyn Rockwood, Chris Gehring
Published 2012-01-01

A genomic portrait of haplotype diversity and signatures of selection in indigenous southern African populations.

by Emile R Chimusa, Ayton Meintjies, Milaine Tchanga, Nicola Mulder, Cathal Seoighe, Himla Soodyall, Rajkumar Ramesar
Published 2015-03-01

Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity

by Paul Geeleher, Aritro Nath, Fan Wang, Zhenyu Zhang, Alvaro N. Barbeira, Jessica Fessler, Robert L. Grossman, Cathal Seoighe, R. Stephanie Huang
Published 2018-09-01

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.

by Natasha Wood, Tanmoy Bhattacharya, Brandon F Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, Guido Ferrari, Barton F Haynes, Andrew McMichael, George M Shaw, Beatrice H Hahn, Bette Korber, Cathal Seoighe
Published 2009-05-01

Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage.

by Denis R Chopera, Zenda Woodman, Koleka Mlisana, Mandla Mlotshwa, Darren P Martin, Cathal Seoighe, Florette Treurnicht, Debra Assis de Rosa, Winston Hide, Salim Abdool Karim, Clive M Gray, Carolyn Williamson, CAPRISA 002 Study Team
Published 2008-03-01

The future of genomics in Ireland – focus on genomics for health [version 1; peer review: 2 approved]

by Cathal Seoighe, Adrian P. Bracken, Patrick Buckley, Peter Doran, Robert Green, Sandra Healy, David Kavanagh, Elaine Kenny, Mark Lawler, Maeve Lowery, Derek Morris, Darrin Morrissey, James J. O'Byrne, Denis Shields, Owen Smith, Charles A. Steward, Brian Sweeney, Walter Kolch
Published 2020-12-01