Viral quasispecies.

by Esteban Domingo, Celia Perales
Published 2019-10-01

Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment.

by Celia Perales, Rubén Agudo, Esteban Domingo
Published 2009-01-01

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus.

by Armando Arias, Celia Perales, Cristina Escarmís, Esteban Domingo
Published 2010-01-01

Mutation Rates, Mutation Frequencies, and Proofreading-Repair Activities in RNA Virus Genetics

by Esteban Domingo, Carlos García-Crespo, Rebeca Lobo-Vega, Celia Perales
Published 2021-09-01

Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections.

by Celia Perales, Rubén Agudo, Hector Tejero, Susanna C Manrubia, Esteban Domingo
Published 2009-11-01

Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications

by Celia Perales, Josep Quer, Josep Gregori, Juan Ignacio Esteban, Esteban Domingo
Published 2015-11-01

Rare haplotype load as marker for lethal mutagenesis.

by Josep Gregori, María Eugenia Soria, Isabel Gallego, Mercedes Guerrero-Murillo, Juan Ignacio Esteban, Josep Quer, Celia Perales, Esteban Domingo
Published 2018-01-01

Viral genome segmentation can result from a trade-off between genetic content and particle stability.

by Samuel Ojosnegros, Juan García-Arriaza, Cristina Escarmís, Susanna C Manrubia, Celia Perales, Armando Arias, Mauricio García Mateu, Esteban Domingo
Published 2011-03-01

A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.

by Rubén Agudo, Cristina Ferrer-Orta, Armando Arias, Ignacio de la Higuera, Celia Perales, Rosa Pérez-Luque, Nuria Verdaguer, Esteban Domingo
Published 2010-08-01

Extinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesis.

by Ana M Ortega-Prieto, Julie Sheldon, Ana Grande-Pérez, Héctor Tejero, Josep Gregori, Josep Quer, Juan I Esteban, Esteban Domingo, Celia Perales
Published 2013-01-01

Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.

by Ana I de Ávila, Isabel Gallego, Maria Eugenia Soria, Josep Gregori, Josep Quer, Juan Ignacio Esteban, Charles M Rice, Esteban Domingo, Celia Perales
Published 2016-01-01

Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants.

by Josep Gregori, Juan I Esteban, María Cubero, Damir Garcia-Cehic, Celia Perales, Rosario Casillas, Miguel Alvarez-Tejado, Francisco Rodríguez-Frías, Jaume Guardia, Esteban Domingo, Josep Quer
Published 2013-01-01

Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks

by Carlos García-Crespo, María Eugenia Soria, Isabel Gallego, Ana Isabel de Ávila, Brenda Martínez-González, Lucía Vázquez-Sirvent, Jordi Gómez, Carlos Briones, Josep Gregori, Josep Quer, Celia Perales, Esteban Domingo
Published 2020-10-01

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies.

by Verónica Martín, Celia Perales, María Fernández-Algar, Helena G Dos Santos, Patricia Garrido, María Pernas, Víctor Parro, Miguel Moreno, Javier García-Pérez, José Alcamí, José Luis Torán, David Abia, Esteban Domingo, Carlos Briones
Published 2016-01-01

Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus

by María Eugenia Soria, Josep Gregori, Qian Chen, Damir García-Cehic, Meritxell Llorens, Ana I. de Ávila, Nathan M. Beach, Esteban Domingo, Francisco Rodríguez-Frías, María Buti, Rafael Esteban, Juan Ignacio Esteban, Josep Quer, Celia Perales
Published 2018-09-01

Population Disequilibrium as Promoter of Adaptive Explorations in Hepatitis C Virus

by Carlos García-Crespo, Isabel Gallego, María Eugenia Soria, Ana Isabel de Ávila, Brenda Martínez-González, Lucía Vázquez-Sirvent, Rebeca Lobo-Vega, Elena Moreno, Jordi Gómez, Carlos Briones, Josep Gregori, Josep Quer, Esteban Domingo, Celia Perales
Published 2021-04-01

Partial restoration of immune response in Hepatitis C patients after viral clearance by direct-acting antiviral therapy.

by Meritxell Llorens-Revull, Maria Isabel Costafreda, Angie Rico, Mercedes Guerrero-Murillo, Maria Eugenia Soria, Sofía Píriz-Ruzo, Elena Vargas-Accarino, Pablo Gabriel-Medina, Francisco Rodríguez-Frías, Mar Riveiro-Barciela, Celia Perales, Josep Quer, Silvia Sauleda, Juan Ignacio Esteban, Marta Bes
Published 2021-01-01