T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells

by Aakanksha Jain, Ran Song, Edward K. Wakeland, Chandrashekhar Pasare
Published 2018-08-01

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming

by Margaret M. McDaniel, Leah C. Kottyan, Harinder Singh, Chandrashekhar Pasare
Published 2020-05-01

Allergen-Induced C5a/C5aR1 Axis Activation in Pulmonary CD11b⁺ cDCs Promotes Pulmonary Tolerance through Downregulation of CD40

by Konstantina Antoniou, Fanny Ender, Tillman Vollbrandt, Yves Laumonnier, Franziska Rathmann, Chandrashekhar Pasare, Harinder Singh, Jörg Köhl
Published 2020-01-01

The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense

by Shuiqing Hu, Lan Peng, Youn-Tae Kwak, Erin McElvania Tekippe, Chandrashekhar Pasare, James S. Malter, Lora V. Hooper, Md. Hasan Zaki
Published 2015-12-01

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

by Ran Song, Yajing Gao, Igor Dozmorov, Venkat Malladi, Irene Saha, Margaret M. McDaniel, Sreeja Parameswaran, Chaoying Liang, Carlos Arana, Bo Zhang, Benjamin Wakeland, Jinchun Zhou, Matthew T. Weirauch, Leah C. Kottyan, Edward K. Wakeland, Chandrashekhar Pasare
Published 2021-03-01

Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus

by Prithvi Raj, Ran Song, Honglin Zhu, Linley Riediger, Dong-Jae Jun, Chaoying Liang, Carlos Arana, Bo Zhang, Yajing Gao, Benjamin E. Wakeland, Igor Dozmorov, Jinchun Zhou, Jennifer A. Kelly, Bernard R. Lauwerys, Joel M. Guthridge, Nancy J. Olsen, Swapan K. Nath, Chandrashekhar Pasare, Nicolai van Oers, Gary Gilkeson, Betty P. Tsao, Patrick M. Gaffney, Peter K. Gregersen, Judith A. James, Xiaoxia Zuo, David R. Karp, Quan-Zhen Li, Edward K. Wakeland
Published 2020-11-01

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

by Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland
Published 2016-02-01