Biomechanical Characterization of Endothelial Cells Exposed to Shear Stress Using Acoustic Force Spectroscopy

by Giulia Silvani, Valentin Romanov, Charles D. Cox, Charles D. Cox, Boris Martinac, Boris Martinac
Published 2021-02-01

Biophysical Principles of Ion-Channel-Mediated Mechanosensory Transduction

by Charles D. Cox, Navid Bavi, Boris Martinac
Published 2019-10-01

Surface model of the human red blood cell simulating changes in membrane curvature under strain

by Philip W. Kuchel, Charles D. Cox, Daniel Daners, Dmitry Shishmarev, Petrik Galvosas
Published 2021-07-01

Enhanced Ca2+ influx in mechanically distorted erythrocytes measured with 19F nuclear magnetic resonance spectroscopy

by Philip W. Kuchel, Konstantin Romanenko, Dmitry Shishmarev, Petrik Galvosas, Charles D. Cox
Published 2021-02-01

Influence of Global and Local Membrane Curvature on Mechanosensitive Ion Channels: A Finite Element Approach

by Omid Bavi, Charles D. Cox, Manouchehr Vossoughi, Reza Naghdabadi, Yousef Jamali, Boris Martinac
Published 2016-02-01

Piezo1 Channels Are Inherently Mechanosensitive

by Ruhma Syeda, Maria N. Florendo, Charles D. Cox, Jennifer M. Kefauver, Jose S. Santos, Boris Martinac, Ardem Patapoutian
Published 2016-11-01

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

by Charles D. Cox, Chilman Bae, Lynn Ziegler, Silas Hartley, Vesna Nikolova-Krstevski, Paul R. Rohde, Chai-Ann Ng, Frederick Sachs, Philip A. Gottlieb, Boris Martinac
Published 2016-01-01

The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

by Navid Bavi, D. Marien Cortes, Charles D. Cox, Paul R. Rohde, Weihong Liu, Joachim W. Deitmer, Omid Bavi, Pavel Strop, Adam P. Hill, Douglas Rees, Ben Corry, Eduardo Perozo, Boris Martinac
Published 2016-06-01

Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations

by Jinyuan Vero Li, Chai-Ann Ng, Delfine Cheng, Zijing Zhou, Mingxi Yao, Yang Guo, Ze-Yan Yu, Yogambha Ramaswamy, Lining Arnold Ju, Philip W. Kuchel, Michael P. Feneley, Diane Fatkin, Charles D. Cox
Published 2021-09-01

The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

by Yang Guo, Ze-Yan Yu, Jianxin Wu, Hutao Gong, Scott Kesteven, Siiri E Iismaa, Andrea Y Chan, Sara Holman, Silvia Pinto, Andy Pironet, Charles D Cox, Robert M Graham, Rudi Vennekens, Michael P Feneley, Boris Martinac
Published 2021-06-01

TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration

by Amrutha Patkunarajah, Jeffrey H Stear, Mirko Moroni, Lioba Schroeter, Jedrzej Blaszkiewicz, Jacqueline LE Tearle, Charles D Cox, Carina Fürst, Oscar Sánchez-Carranza, María del Ángel Ocaña Fernández, Raluca Fleischer, Murat Eravci, Christoph Weise, Boris Martinac, Maté Biro, Gary R Lewin, Kate Poole
Published 2020-03-01

Endocardial TRPC-6 Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk

by Vesna Nikolova-Krstevski, PhD, Soeren Wagner, MD, Ze Yan Yu, MD, Charles D. Cox, PhD, Jasmina Cvetkovska, BSc, Adam P. Hill, PhD, Inken G. Huttner, MD, Victoria Benson, PhD, Andreas A. Werdich, PhD, Calum MacRae, MD, PhD, Michael P. Feneley, MD, PhD, Oliver Friedrich, PhD, Boris Martinac, PhD, Diane Fatkin, MD
Published 2017-10-01