Cardiac regeneration using pluripotent stem cells—Progression to large animal models

by James J.H. Chong, Charles E. Murry
Published 2014-11-01

In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts

by Shin Kadota, Lil Pabon, Hans Reinecke, Charles E. Murry
Published 2017-02-01

Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettes.

by Nathan J Palpant, Peter Hofsteen, Lil Pabon, Hans Reinecke, Charles E Murry
Published 2015-01-01

Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts.

by Kaytlyn A Gerbin, Xiulan Yang, Charles E Murry, Kareen L K Coulombe
Published 2015-01-01

Delta-1 Functionalized Hydrogel Promotes hESC-Cardiomyocyte Graft Proliferation and Maintains Heart Function Post-Injury

by Kaytlyn A. Gerbin, Katie A. Mitzelfelt, Xuan Guan, Amy M. Martinson, Charles E. Murry
Published 2020-06-01

Ferritin Overexpression for Noninvasive Magnetic Resonance Imaging–Based Tracking of Stem Cells Transplanted into the Heart

by Anna V. Naumova, Hans Reinecke, Vasily Yarnykh, Jennifer Deem, Chun Yuan, Charles E. Murry
Published 2010-07-01

Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells.

by Sharon L Paige, Tomoaki Osugi, Olga K Afanasiev, Lil Pabon, Hans Reinecke, Charles E Murry
Published 2010-06-01

Engineered Biomaterials Control Differentiation and Proliferation of Human-Embryonic-Stem-Cell-Derived Cardiomyocytes via Timed Notch Activation

by Jason C. Tung, Sharon L. Paige, Buddy D. Ratner, Charles E. Murry, Cecilia M. Giachelli
Published 2014-03-01

ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells

by Peter Hofsteen, Aaron Mark Robitaille, Nicholas Strash, Nathan Palpant, Randall T. Moon, Lil Pabon, Charles E. Murry
Published 2018-04-01

Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model.

by Ena Ray Banerjee, Michael A Laflamme, Thalia Papayannopoulou, Michael Kahn, Charles E Murry, William R Henderson
Published 2012-01-01

Quantitative Analyses of the Left Ventricle Volume and Cardiac Function in Normal and Infarcted Yucatan Minipigs

by Anna V. Naumova, Gregory Kicska, Kiana Pimentel, Lauren E. Neidig, Hiroshi Tsuchida, Kenta Nakamura, Charles E. Murry
Published 2021-07-01

Targeted genomic integration of a selectable floxed dual fluorescence reporter in human embryonic stem cells.

by Jay A Gantz, Nathan J Palpant, Robert E Welikson, Stephen D Hauschka, Charles E Murry, Michael A Laflamme
Published 2012-01-01

The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?

by Roger A. Barker, Melissa K. Carpenter, Stuart Forbes, Steven A. Goldman, Catriona Jamieson, Charles E. Murry, Jun Takahashi, Gordon Weir
Published 2018-05-01

Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted rat hearts

by Meredith A. Redd, Nicole Zeinstra, Wan Qin, Wei Wei, Amy Martinson, Yuliang Wang, Ruikang K. Wang, Charles E. Murry, Ying Zheng
Published 2019-02-01

Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair

by Sarah Fernandes, James J.H. Chong, Sharon L. Paige, Mineo Iwata, Beverly Torok-Storb, Gordon Keller, Hans Reinecke, Charles E. Murry
Published 2015-11-01

Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory

by Alessandro Bertero, Paul A. Fields, Vijay Ramani, Giancarlo Bonora, Galip G. Yardimci, Hans Reinecke, Lil Pabon, William S. Noble, Jay Shendure, Charles E. Murry
Published 2019-04-01

Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts.

by Jill J Weyers, Jagadambika J Gunaje, Benjamin Van Biber, Amy Martinson, Hans Reinecke, William M Mahoney, Stephen M Schwartz, Timothy C Cox, Charles E Murry
Published 2020-01-01

Evidence that gene activation and silencing during stem cell differentiation requires a transcriptionally paused intermediate state.

by Jonathan L Golob, Roshan M Kumar, Matthew G Guenther, Lil M Pabon, Gabriel A Pratt, Jeanne F Loring, Louise C Laurent, Richard A Young, Charles E Murry
Published 2011-01-01

Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis

by Nathan J. Palpant, Yuliang Wang, Brandon Hadland, Rebecca J. Zaunbrecher, Meredith Redd, Daniel Jones, Lil Pabon, Rajan Jain, Jonathan Epstein, Walter L. Ruzzo, Ying Zheng, Irwin Bernstein, Adam Margolin, Charles E. Murry
Published 2017-08-01

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy

by Nicolò Salvarani, Silvia Crasto, Michele Miragoli, Alessandro Bertero, Marianna Paulis, Paolo Kunderfranco, Simone Serio, Alberto Forni, Carla Lucarelli, Matteo Dal Ferro, Veronica Larcher, Gianfranco Sinagra, Paolo Vezzoni, Charles E. Murry, Giuseppe Faggian, Gianluigi Condorelli, Elisa Di Pasquale
Published 2019-05-01