Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM™ model of NASH.

by Daniela Carmen Oniciu, Taishi Hashiguchi, Yuichiro Shibazaki, Charles L Bisgaier
Published 2018-01-01

Gemcabene, a First-in-Class Hypolipidemic Small Molecule in Clinical Development, Attenuates Osteoarthritis and Pain in Animal Models of Arthritis and Pain

by Rai A. K. Srivastava, Joseph A. Cornicelli, Bruce Markham, Charles L. Bisgaier
Published 2018-05-01

Effects of a novel dual lipid synthesis inhibitor and its potential utility in treating dyslipidemia and metabolic syndrome

by Clay T. Cramer, Brian Goetz, Krista L.M. Hopson, Gregory J. Fici, Rose M. Ackermann, Stephen C. Brown, Charles L. Bisgaier, W.G. Rajeswaran, Daniela C. Oniciu, Michael E. Pape
Published 2004-07-01

A novel compound that elevates high density lipoprotein and activates the peroxisome proliferator activated receptor

by Charles L. Bisgaier, Arnold D. Essenburg, Blake C. Barnett, Bruce J. Auerbach, Sabine Haubenwallner, Todd Leff, Andrew D. White, Paul Creger, Michael E. Pape, Thomas J. Rea, Roger S. Newton
Published 1998-01-01