Utility of the Biosynthetic Folate Pathway for Targets in Antimicrobial Discovery

by Christina R. Bourne
Published 2014-01-01

Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways

by Meenakumari Muthuramalingam, John C. White, Christina R. Bourne
Published 2016-07-01

A YoeB toxin cleaves both RNA and DNA

by Julia McGillick, Jessica R. Ames, Tamiko Murphy, Christina R. Bourne
Published 2021-02-01

Identifying a Molecular Mechanism That Imparts Species-Specific Toxicity to YoeB Toxins

by Jessica R. Ames, Julia McGillick, Tamiko Murphy, Eswar Reddem, Christina R. Bourne
Published 2020-05-01

Expression of different ParE toxins results in conserved phenotypes with distinguishable classes of toxicity

by Jessica R. Ames, Meenakumari Muthuramalingam, Tamiko Murphy, Fares Z. Najar, Christina R. Bourne
Published 2019-10-01

Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex

by Nagendra Prasad Muddala, Baskar Nammalwar, Subhashini Selvaraju, Christina R. Bourne, Mary Henry, Richard A. Bunce, K. Darrell Berlin, Esther W. Barrow, William W. Barrow
Published 2015-04-01

Synthesis and Biological Evaluation of 2,4-Diaminopyrimidine-Based Antifolate Drugs against Bacillus anthracis

by Baskar Nammalwar, N. Prasad Muddala, Christina R. Bourne, Mary Henry, Philip C. Bourne, Richard A. Bunce, Esther W. Barrow, K. Darrell Berlin, William W. Barrow
Published 2014-03-01